Non-coding RNA networks in cancer
E Anastasiadou, LS Jacob, FJ Slack - Nature Reviews Cancer, 2018 - nature.com
Thousands of unique non-coding RNA (ncRNA) sequences exist within cells. Work from the
past decade has altered our perception of ncRNAs from'junk'transcriptional products to …
past decade has altered our perception of ncRNAs from'junk'transcriptional products to …
Functional long non-coding RNAs evolve from junk transcripts
AF Palazzo, EV Koonin - Cell, 2020 - cell.com
Transcriptome studies reveal pervasive transcription of complex genomes, such as those of
mammals. Despite popular arguments for functionality of most, if not all, of these transcripts …
mammals. Despite popular arguments for functionality of most, if not all, of these transcripts …
RNA N6‐methyladenosine methyltransferase‐like 3 promotes liver cancer progression through YTHDF2‐dependent posttranscriptional silencing of SOCS2
Epigenetic alterations have contributed greatly to human carcinogenesis. Conventional
epigenetic studies have predominantly focused on DNA methylation, histone modifications …
epigenetic studies have predominantly focused on DNA methylation, histone modifications …
History, discovery, and classification of lncRNAs
J Jarroux, A Morillon, M Pinskaya - Long non coding RNA biology, 2017 - Springer
Abstract The RNA World Hypothesis suggests that prebiotic life revolved around RNA
instead of DNA and proteins. Although modern cells have changed significantly in 4 billion …
instead of DNA and proteins. Although modern cells have changed significantly in 4 billion …
Transcriptional and post-transcriptional gene regulation by long non-coding RNA
IM Dykes, C Emanueli - Genomics, Proteomics and …, 2017 - academic.oup.com
Advances in genomics technology over recent years have led to the surprising discovery
that the genome is far more pervasively transcribed than was previously appreciated. Much …
that the genome is far more pervasively transcribed than was previously appreciated. Much …
Nuclear long noncoding RNAs: key regulators of gene expression
A significant portion of the human genome encodes genes that transcribe long nonprotein-
coding RNAs (lncRNAs). A large number of lncRNAs localize in the nucleus, either enriched …
coding RNAs (lncRNAs). A large number of lncRNAs localize in the nucleus, either enriched …
Genome-wide analysis of human long noncoding RNAs: a provocative review
CP Ponting, W Haerty - Annual review of genomics and human …, 2022 - annualreviews.org
Do long noncoding RNAs (lncRNAs) contribute little or substantively to human biology? To
address how lncRNA loci and their transcripts, structures, interactions, and functions …
address how lncRNA loci and their transcripts, structures, interactions, and functions …
Distinct processing of lncRNAs contributes to non-conserved functions in stem cells
Long noncoding RNAs (lncRNAs) evolve more rapidly than mRNAs. Whether conserved
lncRNAs undergo conserved processing, localization, and function remains unexplored. We …
lncRNAs undergo conserved processing, localization, and function remains unexplored. We …
The how and why of lncRNA function: an innate immune perspective
EK Robinson, S Covarrubias, S Carpenter - Biochimica et Biophysica Acta …, 2020 - Elsevier
Next-generation sequencing has provided a more complete picture of the composition of the
human transcriptome indicating that much of the “blueprint” is a vastness of poorly …
human transcriptome indicating that much of the “blueprint” is a vastness of poorly …
Analyzing miRNA–lncRNA interactions
MD Paraskevopoulou, AG Hatzigeorgiou - Long non-coding RNAs …, 2016 - Springer
Long noncoding RNAs (lncRNAs) are noncoding transcripts usually longer than 200 nts that
have recently emerged as one of the largest and significantly diverse RNA families. The …
have recently emerged as one of the largest and significantly diverse RNA families. The …