F-box and WD repeat domain-containing 7 (FBXW7), formerly known as hCdc4, hAGO
Fbw7, or SEL10, plays a specific recognition function in SCF-type E3 ubiquitin ligases …

Background: Esophageal cancer (EC) is one of the most common malignant tumors of the
digestive system. MiR-25-3p was proved to be a biomarker for the diagnosis and treatment …

BACKGROUND Heat shock proteins (HSPs) are molecular chaperones that play an
important role in cellular protection against stress events and have been reported to be …

In this editorial we comment on the article published in a recent issue of the World Journal of
Gastrointestinal Oncology. Characterized by high mortality rates and geographical variations …

Esophageal squamous cell carcinoma (ESCC) accounts for the main esophageal cancer
type, which is related to advanced stage and poor survivals. Therefore, novel diagnostic …

Background Neoadjuvant therapy is recommended to improve the prognosis of
oesophageal squamous cell carcinoma (ESCC). As a PD-1 inhibitor developed in China …

Background A clinical challenge in esophageal squamous cell carcinoma (ESCC) remains
the lack of applicable plasma biomarkers for screening and diagnosis. Circular RNAs …

Background F-box protein 45 (FBXO45) is a member of the F-box protein family, and is
reportedly involved in the progression of many diseases. However, its role in esophageal …

To confirm the relationship between Circ_0003855 and EC, we purchased the Human
esophageal carcinoma cell line Eca109 and normal human esophageal epithelial cells …

Esophageal cancer is a major global health challenge with a poor prognosis. Recent studies
underscore the extracellular matrix (ECM) role in cancer progression, but the full impact of …