Age-related macular degeneration
EK de Jong, MJ Geerlings, AI den Hollander - Genetics and genomics of …, 2020 - Elsevier
Age-related macular degeneration (AMD) is a multifactorial disease influenced by a
combination of environmental factors and genetic variants. Genomic studies have been …
combination of environmental factors and genetic variants. Genomic studies have been …
The hypothetical molecular mechanism of the ethnic variations in the manifestation of age-related macular degeneration; focuses on the functions of the most …
S Honda, N Misawa, Y Sato, D Oikawa… - Graefe's Archive for …, 2024 - Springer
Age-related macular degeneration (AMD) is the leading sight-threatening disease in
developed countries. On the other hand, recent studies indicated an ethnic variation in the …
developed countries. On the other hand, recent studies indicated an ethnic variation in the …
Single-cell multiome of the human retina and deep learning nominate causal variants in complex eye diseases
Genome-wide association studies (GWASs) of eye disorders have identified hundreds of
genetic variants associated with ocular disease. However, the vast majority of these variants …
genetic variants associated with ocular disease. However, the vast majority of these variants …
Genome-wide association study of age-related macular degeneration reveals 2 new loci implying shared genetic components with central serous chorioretinopathy
Purpose To investigate the genetic architecture of age-related macular degeneration (AMD)
in a Japanese population. Design Genome-wide association study (GWAS). Participants …
in a Japanese population. Design Genome-wide association study (GWAS). Participants …
Associations of ARMS2 and CFH Gene Polymorphisms with Neovascular Age-Related Macular Degeneration
S Supanji, DF Romdhoniyyah, MB Sasongko… - Clinical …, 2021 - Taylor & Francis
Purpose This study aimed to determine the association of ARMS2 A69S, ARMS2
del443ins54, and CFH Y402H polymorphisms with neovascular age-related macular …
del443ins54, and CFH Y402H polymorphisms with neovascular age-related macular …
[HTML][HTML] High-temperature requirement A 1 causes photoreceptor cell death in zebrafish disease models
Y Oura, M Nakamura, T Takigawa, Y Fukushima… - The American Journal of …, 2018 - Elsevier
Age-related macular degeneration (AMD) is an important cause of blindness. It is
characterized by a retinal pigment epithelium (RPE) disorder that leads to death of …
characterized by a retinal pigment epithelium (RPE) disorder that leads to death of …
Short-term duration of diabetic retinopathy as a predictor for development of diabetic kidney disease
J Duan, D Liu, Z Zhao, L Liang, S Pan… - Journal of …, 2023 - degruyter.com
Background Diabetic retinopathy (DR) is a risk factor for diabetic kidney disease (DKD).
Whether the duration, especially the short-term duration, of DR is associated with the …
Whether the duration, especially the short-term duration, of DR is associated with the …
Genetic analysis of CFH and MCP in Egyptian patients with immune-complex proliferative glomerulonephritis
Glomerulonephritis (GN) is a complex disease with intricate underlying pathogenic
mechanisms. The possible role of underlying complement dysregulation is not fully …
mechanisms. The possible role of underlying complement dysregulation is not fully …
Analysis of genetic polymorphisms for age-related macular degeneration (AMD) in Chinese Tujia ethnic minority group
S Liu, M Wu, B Zhang, X Xiong, H Wang, X Zhou - BMC Medical Genetics, 2019 - Springer
Background Age-related macular degeneration (AMD) can cause vision loss or blindness in
elderly. The associations between single nucleotide polymorphism (SNP) and AMD in …
elderly. The associations between single nucleotide polymorphism (SNP) and AMD in …
Association of ARMS2, HTRA1 and CFH genes polymorphisms in patients with age-related macular degeneration in the Malaysian population
F Ismail, SM Junit, LC Chin, JJ Jayapalan… - Egyptian Journal of …, 2024 - Springer
Background Despite extensive research efforts, understanding the precise causes and
molecular underpinnings of age-related macular degeneration (AMD) remains elusive …
molecular underpinnings of age-related macular degeneration (AMD) remains elusive …