Atrial fibrillation from the pathologist's perspective

D Corradi - Cardiovascular pathology, 2014 - Elsevier
Atrial fibrillation (AF), the most common sustained cardiac arrhythmia encountered in clinical
practice, is associated with increased morbidity and mortality. Electrophysiologically, it is …

Genetics of atrial fibrillation: from families to genomes

IE Christophersen, PT Ellinor - Journal of human genetics, 2016 - nature.com
Atrial fibrillation (AF) is the most common cardiac rhythm disorder and the prevalence is
increasing. The disease confers an increased risk of severe complications such as heart …

[HTML][HTML] Transcriptomics-based network medicine approach identifies metformin as a repurposable drug for atrial fibrillation

JC Lal, C Mao, Y Zhou, SR Gore-Panter… - Cell Reports …, 2022 - cell.com
Effective drugs for atrial fibrillation (AF) are lacking, resulting in significant morbidity and
mortality. This study demonstrates that network proximity analysis of differentially expressed …

Emerging directions in the genetics of atrial fibrillation

NR Tucker, PT Ellinor - Circulation research, 2014 - Am Heart Assoc
Atrial fibrillation (AF) is the most common arrhythmia and is associated with increased
morbidity. As the population ages and the prevalence of AF continues to rise, the …

Genomic basis of atrial fibrillation

A Bapat, CD Anderson, PT Ellinor, SA Lubitz - Heart, 2018 - heart.bmj.com
Atrial fibrillation (AF) is a prevalent arrhythmia associated with substantial morbidity,
mortality and costs. Available management strategies generally have limited efficacy and …

Ethnic differences in atrial fibrillation identified using implanted cardiac devices

CHUPAK LAU, TD Gbadebo… - Journal of …, 2013 - Wiley Online Library
Ethnic Difference in Atrial Fibrillation Incidence. Introduction: Atrial fibrillation (AF) is
suggested to be less common among black and Asian individuals, which could reflect bias …

Genetics of atrial fibrillation

SA Lubitz, BA Yi, PT Ellinor - Cardiology clinics, 2009 - Elsevier
Recent studies of AF have identified mutations in a series of ion channels; however, these
mutations appear to be relatively rare causes of AF. A genome-wide association study has …

Genome-wide association studies of cardiac electrical phenotypes

C Glinge, N Lahrouchi, R Jabbari… - Cardiovascular …, 2020 - academic.oup.com
The genetic basis of cardiac electrical phenotypes has in the last 25 years been the subject
of intense investigation. While in the first years, such efforts were dominated by the study of …

Scarcity of atrial fibrillation in a traditional African population: a community-based study

JJE Koopman, D van Bodegom… - BMC cardiovascular …, 2014 - Springer
Background In western societies, atrial fibrillation is an increasingly common finding among
the elderly. Established risk factors of atrial fibrillation include obesity, diabetes …

A clinical prediction model for postcardiac surgery atrial fibrillation in an Asian population

W Zhang, W Liu, STH Chew, L Shen… - Anesthesia & Analgesia, 2016 - journals.lww.com
BACKGROUND: Postoperative atrial fibrillation (AF) is associated with increased morbidity,
mortality, and resource utilization. Current prediction models for postoperative AF are based …