Microbiome and metabolome features of the cardiometabolic disease spectrum

S Fromentin, SK Forslund, K Chechi… - Nature medicine, 2022 - nature.com
Previous microbiome and metabolome analyses exploring non-communicable diseases
have paid scant attention to major confounders of study outcomes, such as common, pre …

Ultrahigh-resolution NMR with water signal suppression for a deeper understanding of the action of antimetabolic drugs on diffuse large B-cell lymphoma

G Bertho, L Lordello, X Chen… - Journal of Proteome …, 2022 - ACS Publications
Ultrahigh-resolution NMR has recently attracted considerable attention in the field of
complex samples analysis. Indeed, the implementation of broadband homonuclear …

Current developments in homonuclear and heteronuclear J‐resolved NMR experiments

T Parella - Magnetic Resonance in Chemistry, 2018 - Wiley Online Library
Two‐dimensional J‐resolved (J res) NMR experiments offer a simple, user‐friendly spectral
representation where the information of coupling constants and chemical shifts are …

Present and future of pure shift NMR in metabolomics

X Chen, G Bertho, C Caradeuc… - Magnetic …, 2023 - Wiley Online Library
NMR is one of the most powerful techniques for the analysis of biological samples in the
field of metabolomics. However, the high complexity of fluids, tissues, or other biological …

Using neural networks to obtain NMR spectra of both small and macromolecules from blood samples in a single experiment

X Xiao, Q Wang, X Chai, X Zhang, B Jiang… - Communications …, 2024 - nature.com
Metabolomics plays a crucial role in understanding metabolic processes within biological
systems. Using specific pulse sequences, NMR-based metabolomics detects small and …

SMolESY: An efficient and quantitative alternative to on-instrument macromolecular 1 H-NMR signal suppression

PG Takis, B Jiménez, CJ Sands, E Chekmeneva… - Chemical …, 2020 - pubs.rsc.org
One-dimensional (1D) proton-nuclear magnetic resonance (1H-NMR) spectroscopy is an
established technique for measuring small molecules in a wide variety of complex biological …

InterSpin: Integrated supportive webtools for low-and high-field NMR analyses toward molecular complexity

S Yamada, K Ito, A Kurotani, Y Yamada… - ACS …, 2019 - ACS Publications
InterSpin (http://dmar. riken. jp/interspin/) comprises integrated, supportive, and freely
accessible preprocessing webtools and a database to advance signal assignment in low …

Tackling the Peak Overlap Issue in NMR Metabolomics Studies: 1D Projected Correlation Traces from Statistical Correlation Analysis on Nontilted 2D 1H NMR J …

A Charris-Molina, G Riquelme, P Burdisso… - Journal of proteome …, 2019 - ACS Publications
The identification of metabolites in complex biological matrices is a challenging task in 1D
1H-NMR-based metabolomics studies. Statistical total correlation spectroscopy (STOCSY) …

PSYCHE—a valuable experiment in plant NMR-metabolomics

P Stark, C Zab, A Porzel, K Franke, P Rizzo… - Molecules, 2020 - mdpi.com
1H-NMR is a very reproducible spectroscopic method and, therefore, a powerful tool for the
metabolomic analysis of biological samples. However, due to the high complexity of natural …

Multiplet-Assisted Peak Alignment for 1H NMR-Based Metabolomics

A Charris-Molina, P Burdisso… - Journal of Proteome …, 2023 - ACS Publications
NMR-based metabolomics aims at recovering biological information by comparing spectral
data from samples of biological interest and appropriate controls. Any statistical analysis …