[HTML][HTML] Recent advances in the piperazine based antiviral agents: A remarkable heterocycle for antiviral research

K Walayat, S Aslam, N Rasool, M Ahmad… - Arabian Journal of …, 2023 - Elsevier
A growing interest in pharmacology has made heterocyclic chemistry as one of the emerging
branches of organic chemistry. Piperazine is an excellent heterocycle that possesses a large …

Medicinal Chemistry Perspectives on the Development of Piperazine-Containing HIV-1 Inhibitors

CA Salubi, HS Abbo, N Jahed, S Titinchi - Bioorganic & Medicinal …, 2024 - Elsevier
The Human immunodeficiency virus (HIV) is the causative agent of acquired
immunodeficiency syndrome (AIDS), one of the most perilous diseases known to …

Deep eutectic solvents (des) as green and efficient solvent/catalyst systems for the synthesis of carbamates and ureas from carbonates

I Dindarloo Inaloo, S Majnooni - ChemistrySelect, 2019 - Wiley Online Library
The use of sustainable deep eutectic solvents (DESs) as stable and green solvent/catalyst
systems shows unprecedented high efficiency in the formation of carbamates and ureas …

Experimental and computational investigations of some new cabamothioate compounds

N Shajari, H Yahyaei, A Ramazani - Chemical Review and Letters, 2021 - chemrevlett.com
The new derivatives of S-aryl (trichloroacetyl) carbamothioate were prepared from a two-
component reaction of 2-naphthalenethiol or thiophenol derivatives and trichloroacetyl …

Insights into the HO· and HOO· radical scavenging activity of aryl carbamate derivative: a computational mechanistic and kinetic investigation

C Kaur, D Mandal - Theoretical Chemistry Accounts, 2024 - Springer
Aryl carbamates exhibit significant utility due to their diverse range of biological activities,
including anticancer, antituberculosis, and antioxidant properties. This study will focus on a …

Synthesis and biological activity of new salicylanilide N, N-disubstituted carbamates and thiocarbamates

M Krátký, M Volková, E Novotná, F Trejtnar… - Bioorganic & Medicinal …, 2014 - Elsevier
The development of novel antimicrobial drugs represents a cutting edge research topic. In
this study, 20 salicylanilide N, N-disubstituted carbamates and thiocarbamates were …

Evaluation of antioxidant properties of new functionally substituted aryl carbamates

MN Kolyada, VP Osipova, MA Polovinkina… - AIP Conference …, 2022 - pubs.aip.org
The antioxidative activity of new carbamate derivatives has been compared by studying their
influence on the generation of superoxide anion radical O-• in the enzyme/substrate system …

Radical scavenging mechanism of aryl carbamate: a computational case study using 3-morpholinopropyl phenyl carbamate

C Kaur, D Mandal - Structural Chemistry, 2024 - Springer
A systematic computational mechanistic and kinetics investigation has been performed on
the antioxidant activity of phenyl carbamate, namely 3-morpholinopropyl phenyl carbamate …

Safety profile of AZT derivatives: Organoselenium moieties confer different cytotoxic responses in fresh human erythrocytes during in vitro exposures

A Ecker, RS da Silva, MM Dos Santos… - Journal of Trace …, 2018 - Elsevier
Introduction The incorporation of selenium in the structure of nucleosides is a promising
strategy to develop novel therapeutic molecules. Objective To assess the toxic effects of …

Glycol and Phosphate Depot Forms of 4-and/or 5-Modified Nucleosides Exhibiting Antibacterial Activity

SD Negrya, MV Jasko, DA Makarov, PN Solyev… - Molecular Biology, 2021 - Springer
Resistance developed to the majority of drugs used to treat infectious diseases warrants the
design of new compounds effective against drug-resistant strains of pathogens. Recently …