Purpose To determine the linearity, bias, and precision of hepatic proton density fat fraction
(PDFF) measurements by using magnetic resonance (MR) imaging across different field …

Alcohol abuse is the most common cause of fatty liver disease, but it is now apparent that fat
deposition in the liver, and its consequences, may occur without alcohol abuse. The …

NAD+ is a redox-active metabolite, the depletion of which has been proposed to promote
aging and degenerative diseases in rodents. However, whether NAD+ depletion occurs in …

Weight loss by ketogenic diet (KD) has gained popularity in management of nonalcoholic
fatty liver disease (NAFLD). KD rapidly reverses NAFLD and insulin resistance despite …

The prevalence of obesity in the United States and the world has risen to
epidemic/pandemic proportions. This increase has occurred despite great efforts by …

Purpose To evaluate the diagnostic performance of magnetic resonance (MR) imaging–
estimated proton density fat fraction (PDFF) for assessing hepatic steatosis in nonalcoholic …

Nonalcoholic fatty liver disease (NAFLD) is a burgeoning health problem of unknown
etiology that varies in prevalence among ancestry groups. To identify genetic variants …

Despite the increasing prevalence of nonalcoholic fatty liver disease (NAFLD), its
pathogenesis and clinical significance remain poorly defined. In this study, we examined …

On February 19–22, the 2012 ISMRM Workshop on Fat–Water Separation was held in Long
Beach, California. Over 130 attendees from 13 countries convened to discuss historical …

Background Lifestyle interventions focusing on weight loss remain the cornerstone of non-
alcoholic fatty liver disease (NAFLD) management. Despite this, the weight losses achieved …