Prediction of a Stable Complex of Compounds in the Ethanol Extract of Celery Leaves (Apium graveolens L.) Function as a VKORC1 Antagonist.

A Asnawi, M Nedja, E Febrina… - Tropical Journal of …, 2023 - search.ebscohost.com
The vitamin K cycle, specifically the protein VKORC1 (Vitamin K epoxide reductase complex
subunit 1), is closely linked to coagulation mechanisms in the body. Disruptions in this cycle …

[PDF][PDF] In silico evaluation of the dermal antiaging activity of Molineria latifolia (Dryand. ex WT Aiton) Herb. Ex Kurz compounds

H ex Kurz - Journal of Pharmacy & Pharmacognosy Research, 2023 - jppres.com
Context: Dermal aging is one of the events caused by a decrease in the structure of skin
tissues due to various factors. Molineria latifolia is one of the plants empirically used in …

[PDF][PDF] Hepatoprotective study of Indonesian water kefir against CCl4-induced liver injury in rats

W Aligita, M Singgih, E Sutrisno… - J. Pharm. Pharmacogn …, 2023 - academia.edu
Context: Water kefir is a fermented beverage that is typically made in the home by
inoculating a sugar-rich solution with a microbial community (water kefir grains). Several …

Virtual Screening Using a Ligand-based Pharmacophore Model from Ashitaba (Angelica keiskei K.) Isolates and Molecular Docking to Obtained New Candidates as α …

A Yuliantini, S Ocktavyanie… - Tropical Journal of …, 2024 - search.ebscohost.com
Diabetes mellitus (DM) is a serious, long-term disease when the pancreas doesn't make
enough insulin or when the body can't use the insulin it makes well. Type 2 Diabetes …

A Review of Tannin Compounds in Avocado as Antioxidants.

D Kurnia, D Meilinawati, L Marliani… - Tropical Journal of …, 2024 - search.ebscohost.com
Avocados, a fruit from Persea americana, are highly nutritious and energy-dense. However,
some people eat the tasty fruit and rarely use other plant parts that can benefit their health …

Anti-diabetic drug discovery using the bioactive compounds of Momordica charantia by molecular docking and molecular dynamics analysis

AA Choudhury, M Arumugam… - Journal of …, 2024 - Taylor & Francis
Diabetes mellitus (DM) is a multifactorial life-threatening endocrine disease characterized by
abnormalities in glucose metabolism. It is a chronic metabolic disease that involves multiple …

Molecular Docking Simulation of Reported Phytochemical Compounds from Curculigo latifolia Extract on Target Proteins Related to Skin Antiaging.

S Nur, M Hanafi, H Setiawan… - Tropical Journal of …, 2023 - search.ebscohost.com
Abstract Curculigo latifolia Dryand. Ex WT Alton is a plant reported to have antioxidant and
anti-aging activities. Studies have shown the interaction of compounds from this plant with …

Virtual Screening and Molecular Docking of Traditional Chinese Medicine Database Reveals Curculigoside as a Promising Inhibitor for Non‐Insulin‐Dependent …

MS Hossain, M Roney, MN Uddin… - …, 2025 - Wiley Online Library
Millions worldwide grapple with diabetes mellitus, a global health burden lacking a definitive
cure. The DrugRep, a web program for multi‐database drug discovery, remains unexplored …

Antidiabetic Activities and GC-MS Analysis of 4-Methoxychalcone

LDR Acho, ESC Oliveira, SB Carneiro, FPA Melo… - AppliedChem, 2024 - mdpi.com
Diabetes mellitus is a chronic metabolic disease that is mainly characterized by
hyperglycemia. Chalcones and their derivatives have demonstrated promising …

Integrative computational approaches for designing novel alpha-glucosidase inhibitors based on curculigoside A derivatives: Virtual screening, molecular docking …

A Asnawi, S Mieldianisa, W Aligita… - Journal of …, 2024 - herbmedpharmacol.com
Introduction: Over 422 million people worldwide suffer from diabetes, causing 1.5 million
fatalities annually. The existing medications have shortcomings, including poor glucose …