[HTML][HTML] Research progress of glutathione peroxidase family (GPX) in redoxidation

J Pei, X Pan, G Wei, Y Hua - Frontiers in pharmacology, 2023 - frontiersin.org
Maintaining the balance of a cell's redox function is key to determining cell fate. In the critical
redox system of mammalian cells, glutathione peroxidase (GPX) is the most prominent …

[HTML][HTML] Immunomodulatory roles of selenium nanoparticles: Novel arts for potential immunotherapy strategy development

G Chen, F Yang, S Fan, H Jin, K Liao, X Li… - Frontiers in …, 2022 - frontiersin.org
Current chemotherapy strategies used in clinic appear with lots of disadvantages due to the
low targeting effects of drugs and strong side effects, which significantly restricts the drug …

Selenium deficiency caused fibrosis as an oxidative stress-induced inflammatory injury in the lungs of mice

Y Fu, Y Wang, Q Bu, M Guo - Biological Trace Element Research, 2023 - Springer
Selenium (Se) is a vital trace element in the regulation of inflammation and antioxidant
reactions in both animals and humans. Se deficiency is rapidly affecting lung function. The …

[HTML][HTML] The role of selenium in cell survival and its correlation with protective effects against cardiovascular disease: A literature review

A Shalihat, AN Hasanah, R Lesmana… - Biomedicine & …, 2021 - Elsevier
Selenium is a trace element that provides protection against cellular damage and death.
Previous research using several types of cells identified anti-oxidant, anti-inflammatory, and …

Selenium-containing amino acids protect dextran sulfate sodium-induced colitis via ameliorating oxidative stress and intestinal inflammation

C Shi, F Yue, F Shi, Q Qin, L Wang… - Journal of …, 2021 - Taylor & Francis
Background Inflammatory bowel disease (IBD) is characterized by chronic relapsing
inflammation of the gastrointestinal tract. Oxidative stress plays a pivotal role in the …

[HTML][HTML] The role of selenoprotein tissue homeostasis in MetS programming: energy balance and cardiometabolic implications

ML Ojeda, O Carreras, F Nogales - Antioxidants, 2022 - mdpi.com
Selenium (Se) is an essential trace element mainly known for its antioxidant, anti-
inflammatory, and anti-apoptotic properties, as it is part of the catalytic center of 25 different …

[HTML][HTML] Selenylated Imidazo [1,2-a]pyridine Induces Apoptosis and Oxidative Stress in 2D and 3D Models of Colon Cancer Cells

GB Gomes, CS Zubieta, JS Guilhermi, MC Toffoli-Kadri… - Pharmaceuticals, 2023 - mdpi.com
Colon cancer incidence rates are increasing annually, a scenario aggravated by genetic
and epigenetic alterations that promote drug resistance. Recent studies showed that novel …

Selenium attenuates TBHP‐induced apoptosis of nucleus pulposus cells by suppressing mitochondrial fission through activating nuclear factor erythroid 2‐related …

P Wang, S Zhang, W Liu, S Chen, X Lv… - Oxidative Medicine …, 2022 - Wiley Online Library
Intervertebral disc (IVD) degeneration (IDD), the leading cause of low back pain (LBP),
remains intractable due to a lack of effective therapeutic strategies. Several lines of studies …

[HTML][HTML] Selenomethionine Attenuated H2O2-Induced Oxidative Stress and Apoptosis by Nrf2 in Chicken Liver Cells

L Xie, Y Xu, X Ding, K Li, S Liang, D Li, Y Wang, A Fu… - Antioxidants, 2023 - mdpi.com
Earlier studies have shown that selenomethionine (SM) supplements in broiler breeders had
higher deposition in eggs, further reduced the mortality of chicken embryos, and exerted a …

[HTML][HTML] Erlotinib protests against LPS-induced parthanatos through inhibiting macrophage surface TLR4 expression

Q Xue, X Liu, C Chen, X Zhang, P Xie, Y Liu… - Cell Death …, 2021 - nature.com
Sepsis is a life-threatening cascading systemic inflammatory response syndrome on account
of serve infection. In inflamed tissues, activated macrophages generate large amounts of …