The chronic dysfunction of neuronal cells, both central and peripheral, a characteristic of
neurological disorders, may be caused by irreversible damage and cell death. In 2016, more …

Major depressive disorder (MDD), also known as unipolar depression, is one of the leading
causes of disability and disease worldwide. The signs and symptoms are low self‑esteem …

Abstract Ethnopharmacological relevance Buyang Huanwu Decoction (BYHWD) is used in
classical traditional Chinese medicine to prevent and treat cerebral ischemia. Glycosides …

Depression is a prevalent disease worldwide, limiting psychosocial functioning and
thequality of life. Linalool is the main constituent of some essential oils from aromatic plants …

Abstract Ethnopharmacological relevance Gastrodia elata Bl.(GE) is one of the rare Chinese
medicinal materials with a long history of medicine and cooking. It consists of a variety of …

Background Insomnia and depressive disorder are two common symptoms with a reciprocal
causal relationship in clinical practice, which are usually manifested in comorbid form …

Depression has emerged as a major cause of mortality globally. Many studies have reported
risk factors and mechanisms associated with depression, but it is as yet unclear how these …

Prevention of epilepsy is a great unmet need. Acute central nervous system (CNS) insults
such as traumatic brain injury (TBI), cerebrovascular accidents (CVA), and CNS infections …

Background The complex pathophysiology of epilepsy hampers the development of effective
treatments. Although more than ten kinds of anti-seizures drugs (ASDs) have good effects on …

Post-traumatic epilepsy (PTE) is one of the most devastating long-term, network
consequences of traumatic brain injury (TBI). There is currently no approved treatment that …