Role of phytochemicals in cancer prevention
The use of synthetic, natural, or biological agents to minimize the occurrence of cancer in
healthy individuals is defined as cancer chemoprevention. Chemopreventive agents inhibit …
healthy individuals is defined as cancer chemoprevention. Chemopreventive agents inhibit …
Prostate Cancer Biomarkers: From diagnosis to prognosis and precision-guided therapeutics
M Adamaki, V Zoumpourlis - Pharmacology & therapeutics, 2021 - Elsevier
Prostate cancer (PCa) is one of the most commonly diagnosed malignancies and among the
leading causes of cancer-related death worldwide. It is a highly heterogeneous disease …
leading causes of cancer-related death worldwide. It is a highly heterogeneous disease …
Mechanisms underlying biological effects of cruciferous glucosinolate-derived isothiocyanates/indoles: a focus on metabolic syndrome
M Esteve - Frontiers in Nutrition, 2020 - frontiersin.org
An inverse correlation between vegetable consumption and the incidence of cancer has
long been described. This protective effect is stronger when cruciferous vegetables are …
long been described. This protective effect is stronger when cruciferous vegetables are …
The role of isothiocyanates as cancer chemo-preventive, chemo-therapeutic and anti-melanoma agents
M Mitsiogianni, G Koutsidis, N Mavroudis, DT Trafalis… - Antioxidants, 2019 - mdpi.com
Many studies have shown evidence in support of the beneficial effects of phytochemicals in
preventing chronic diseases, including cancer. Among such phytochemicals, sulphur …
preventing chronic diseases, including cancer. Among such phytochemicals, sulphur …
Dietary isothiocyanates inhibit cancer progression by modulation of epigenome
Cell cycle, growth, survival and metabolism are tightly regulated together and failure in
cellular regulation leads to carcinogenesis. Several signaling pathways like the PI3K, WNT …
cellular regulation leads to carcinogenesis. Several signaling pathways like the PI3K, WNT …
Phytochemicals based chemopreventive and chemotherapeutic strategies and modern technologies to overcome limitations for better clinical applications
Naturally occurring phytochemicals or plant derivatives are now being explored extensively
for their health's benefits and medicinal uses. The therapeutic effect of phytochemicals has …
for their health's benefits and medicinal uses. The therapeutic effect of phytochemicals has …
Prospective epigenetic actions of organo-sulfur compounds against cancer: perspectives and molecular mechanisms
Simple Summary Epigenetics has provided a new dimension to our understanding of cancer
initiation and progression. Unlike the genetic changes in DNA sequence, abnormal …
initiation and progression. Unlike the genetic changes in DNA sequence, abnormal …
Health-promoting role of dietary bioactive compounds through epigenetic modulations: a novel prophylactic and therapeutic approach
The epigenome is an overall epigenetic state of an organism, which is as important as that of
the genome for normal development and functioning of an individual. Epigenetics involves …
the genome for normal development and functioning of an individual. Epigenetics involves …
Association of smoking, alcohol use, and betel quid chewing with epigenetic aberrations in cancers
Numerous environmental factors such as diet, alcohol use, stress, and environmental
chemicals are known to elicit epigenetic changes, leading to increased rates of cancers and …
chemicals are known to elicit epigenetic changes, leading to increased rates of cancers and …
DNMT1-mediated demethylation of lncRNA MEG3 promoter suppressed breast cancer progression by repressing Notch1 signaling pathway
T Pan, H Ding, L Jin, S Zhang, D Wu, W Pan, M Dong… - Cell Cycle, 2022 - Taylor & Francis
Breast carcinoma is one of the common causes of cancer-related mortality in women.
Maternally expressed gene 3 (MEG3), a lncRNA located at 14q32, can be involved in …
Maternally expressed gene 3 (MEG3), a lncRNA located at 14q32, can be involved in …