Structural characterization of transcription-coupled repair protein UVSSA and its interaction with TFIIH protein
UV-stimulated scaffold protein A (UVSSA) is a key protein in the Transcription-Coupled
Nucleotide Excision Repair (TC-NER) pathway. UVSSA, an intrinsically disordered protein …
Nucleotide Excision Repair (TC-NER) pathway. UVSSA, an intrinsically disordered protein …
Indirect routes to aminoacyl-tRNA: The diversity of prokaryotic cysteine encoding systems
Universally present aminoacyl-tRNA synthetases (aaRSs) stringently recognize their
cognate tRNAs and acylate them with one of the proteinogenic amino acids. However, some …
cognate tRNAs and acylate them with one of the proteinogenic amino acids. However, some …
RNA-dependent cysteine biosynthesis in bacteria and archaea
The diversity of the genetic code systems used by microbes on earth is yet to be elucidated.
It is known that certain methanogenic archaea employ an alternative system for cysteine …
It is known that certain methanogenic archaea employ an alternative system for cysteine …
Conformational transitions in human translin enable nucleic acid binding
Translin is a highly conserved RNA-and DNA-binding protein that plays essential roles in
eukaryotic cells. Human translin functions as an octamer, but in the octameric …
eukaryotic cells. Human translin functions as an octamer, but in the octameric …
Translin: A multifunctional protein involved in nucleic acid metabolism
A Gupta, VS Pillai, RK Chittela - Journal of Biosciences, 2019 - Springer
Translin, a highly conserved, DNA/RNA binding protein, is abundantly expressed in brain,
testis and in certain malignancies. It was discovered initially in the quest to find proteins that …
testis and in certain malignancies. It was discovered initially in the quest to find proteins that …
Structural basis for single-stranded RNA recognition and cleavage by C3PO
J Zhang, H Liu, Q Yao, X Yu, Y Chen, R Cui… - Nucleic Acids …, 2016 - academic.oup.com
Translin and translin-associated factor-x are highly conserved in eukaroytes; they can form
heteromeric complexes (known as C3POs) and participate in various nucleic acid …
heteromeric complexes (known as C3POs) and participate in various nucleic acid …
Biochemical characterization of clinically relevant mutations of human Translin
V Pillai, A Gupta, A Rao, RK Chittela - Molecular and Cellular Biochemistry, 2023 - Springer
DNA damage in all living cells is repaired with very high efficiency and nucleic acid binding
proteins play crucial roles in repair associated processes. Translin is one such evolutionarily …
proteins play crucial roles in repair associated processes. Translin is one such evolutionarily …
Characterization of a plant (rice) translin and its comparative analysis with human translin
RK Chittela, GD Gupta, A Ballal - Planta, 2014 - Springer
Main conclusion For the first time, a plant (rice) translin was characterized. The rice translin
protein, which was octameric in native state, bound efficiently to single-stranded DNA and …
protein, which was octameric in native state, bound efficiently to single-stranded DNA and …
[HTML][HTML] Identification of proteins that form specific complexes with the highly conserved protein Translin in Schizosaccharomyces pombe
E Eliahoo, P Litovco, RB Yosef, K Bendalak… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Translin is a single-stranded DNA and RNA binding protein that has a high affinity for G-rich
sequences. TRAX is a Translin paralog that associates with Translin. Both Translin and …
sequences. TRAX is a Translin paralog that associates with Translin. Both Translin and …
C-terminal residues of rice translin are essential for octamer formation and nucleic acid binding
Translin is a DNA/RNA binding protein involved in DNA repair and RNA metabolism.
Previously, we had shown that rice translin (221 amino acids) exhibits biochemical activities …
Previously, we had shown that rice translin (221 amino acids) exhibits biochemical activities …