BACKGROUND: Impaired perineal wound healing has become a significant clinical problem
after abdominoperineal resection for rectal cancer. The increased use of neoadjuvant …

The peritoneal metastatic route of cancer dissemination is shared by cancers of the ovary
and gastrointestinal tract. Once initiated, peritoneal metastasis typically proceeds rapidly in a …

Background Intraoperative tumour perforation, positive tumour margins, wound
complications and local recurrence are frequent difficulties with conventional …

Background Abdominoperineal excision (APE) for low rectal cancer is associated with
higher rates of circumferential resection margin (CRM) involvement and intraoperative …

Purpose Despite the major improvements that have been made due to total mesorectal
excision (TME), low rectal cancer still remains a challenge. Methods By investigating a …

Background Transanal total mesorectal excision (TaTME) has been proposed as an
approach in patients with mid and low rectal cancer. The TaTME procedure has been …

Purpose Abdominoperineal excision (APE) of the rectum and anus for rectal cancer
continues to have greater local recurrence and poorer survival than that seen following …

Objective: The goal was to assess long-term oncologic outcome after laparoscopic versus
open surgery for rectal cancer and to evaluate the impact of conversion. Summary …

Introduction Anastomotic leakage is one of the most severe early complications after
colorectal surgery, and it is associated with a high reoperation rate-, and increased in short …

Background This study examined the prognostic impact of the circumferential resection
margin (CRM) in patients with rectal cancer treated by total mesorectal excision (TME) with …