[HTML][HTML] Deciphering roles of TRIMs as promising targets in hepatocellular carcinoma: current advances and future directions

J Zhang, Y Zhou, J Feng, X Xu, J Wu, C Guo - Biomedicine & …, 2023 - Elsevier
Tripartite motif (TRIM) family is assigned to RING-finger-containing ligases harboring the
largest number of proteins in E3 ubiquitin ligating enzymes. E3 ubiquitin ligases target the …

A programmable targeted protein-degradation platform for versatile applications in mammalian cells and mice

X Ma, J Yin, L Qiao, H Wan, X Liu, Y Zhou, J Wu, L Niu… - Molecular Cell, 2024 - cell.com
Myriad physiological and pathogenic processes are governed by protein levels and
modifications. Controlled protein activity perturbation is essential to studying protein function …