Mutations in melanocortin-4 receptor: From fish to men
YX Tao - Progress in Molecular Biology and Translational …, 2022 - Elsevier
Abstract Melanocortin-4 receptor (MC4R), expressed abundantly in the hypothalamus, is a
critical regulator of energy homeostasis, including both food intake and energy expenditure …
critical regulator of energy homeostasis, including both food intake and energy expenditure …
A binary system based DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells
T Li, M Sun, S Xia, T Huang, RT Li, C Li, Z Dai, JX Chen… - Talanta, 2024 - Elsevier
Developing simple, rapid and specific mRNA imaging strategy plays an important role in the
early diagnosis of cancer and the new drugs development. Herein, we have established a …
early diagnosis of cancer and the new drugs development. Herein, we have established a …
Two co‐inherited novel SNPs in the MC4R gene related to live body weight and hormonal assays in Awassi and Arabi sheep breeds of Iraq
TM Al‐Thuwaini, MBS Al‐Shuhaib… - Veterinary Medicine …, 2021 - Wiley Online Library
Abstract Melanocortin‐4 receptor (MC4R) gene plays a key role in the regulation of body
weight and energy homeostasis. This study aims to evaluate the association of single …
weight and energy homeostasis. This study aims to evaluate the association of single …
NCAPG Regulates Myogenesis in Sheep, and SNPs Located in Its Putative Promoter Region Are Associated with Growth and Development Traits
Z Yuan, L Ge, P Su, Y Gu, W Chen, X Cao, S Wang… - Animals, 2023 - mdpi.com
Simple Summary Screening for polymorphisms in the promoter region of a functional gene is
an effective way to identify useful markers for improving sheep growth and development …
an effective way to identify useful markers for improving sheep growth and development …
[HTML][HTML] A Critical Functional Missense Mutation (T117M) in Sheep MC4R Gene Significantly Leads to Gain-of-Function
Z Zhao, Y Yang, P Liu, T Yan, R Li, C Pan, Y Li, X Lan - Animals, 2024 - mdpi.com
Simple Summary The melanocortin 4 receptor (MC4R) is an important gene that can affect
the growth and economic traits of sheep. This study first investigated the distribution of the …
the growth and economic traits of sheep. This study first investigated the distribution of the …
Novel mutations in the signal transducer and activator of transcription 3 gene are associated with sheep body weight and fatness traits
Y Chong, G Liu, S Girmay, X Jiang - Mammalian Genome, 2021 - Springer
The signal transducer and activator of transcription 3 (STAT3) gene plays a crucial role in
leptin-mediated energy metabolism, upon which the growth and development of animals …
leptin-mediated energy metabolism, upon which the growth and development of animals …
Mitogenome-wide association study on body measurement traits of Wenshang Barred chickens
D Wang, J Teng, C Ning, W Wang, S Liu… - Animal …, 2023 - Taylor & Francis
Mitochondria are best known for synthesizing ATP through the tricarboxylic acid cycle and
oxidative phosphorylation. The cytoplasmic mitochondrial DNA (mtDNA) is important for …
oxidative phosphorylation. The cytoplasmic mitochondrial DNA (mtDNA) is important for …
[HTML][HTML] Association between the Melanocortin-4 Receptor (MC4R) gene polymorphisms and growth trait in Sumba Ongole cattle
Melanocortin-4 receptor (MC4R) gene has been known as a candidate gene for growth traits
in livestock. This research was aimed to identify the polymorphism of MC4R gene and its …
in livestock. This research was aimed to identify the polymorphism of MC4R gene and its …
Integrative single-cell characterization of hypothalamus sex-differential and obesity-associated genes and regulatory elements
Over 500 noncoding genomic loci are associated with obesity. The majority of these loci
reside near genes that are expressed in the hypothalamus in specific neuronal …
reside near genes that are expressed in the hypothalamus in specific neuronal …
Detection of MC4R Gene Genotypes and A Relationship SNP13 to Productive and Reproductive Performance in Iraqi Local Goats and Shami Goats
AAM Al-jburi, RH Senkal - IOP Conference Series: Earth and …, 2023 - iopscience.iop.org
The study was conducted at the Ruminant Research Station of the Agricultural Research
Department/Ministry of Agriculture, for the period from 1/12/2021-30/10/2022, the current …
Department/Ministry of Agriculture, for the period from 1/12/2021-30/10/2022, the current …