This review is aimed at summarizing the new findings about the multiple benefits of exercise
on cardiovascular disease (CVD). We pay attention to the prevalence and risk factors of …

Background Physical activity has been associated with reduced oxidative stress (OS) in
observational studies and clinical trials. Objective The purpose of this systematic review and …

Despite the wealth of epidemiological and experimental studies indicating the protective role
of regular physical activity/exercise training against the sequels of aging and cardiovascular …

The pivotal observation that muscular exercise is associated with oxidative stress in humans
was first reported over 45 years ago. Soon after this landmark finding, it was discovered that …

Background The physiological impairments most strongly associated with functional
performance in older people are logically the most efficient therapeutic targets for exercise …

Epigenetic modification refers to heritable changes in gene function that cannot be
explained by alterations in the DNA sequence. The current literature clearly demonstrates …

Introduction Ageing can be accompanied by increased inflammation, which contributes to
the development of sarcopenia. Exercise training could be effective for preventing …

The practice of physical exercise (PE), especially strength training (ST), has health benefits
in the healthy population; however, the literature is scarce in the recommendations related to …

Cells have evolved multiple and sophisticated stress response mechanisms aiming to
prevent macromolecular (including proteins, lipids, and nucleic acids) damage and to …

All organisms and cells respond to various stress conditions such as environmental,
metabolic, or pathophysiological stress by generally upregulating, among others, the …