Toxic heavy metals (THMs) are non-essential hazardous environmental pollutants with
intractable health challenges in humans and animals. Exposure to lead (Pb), cadmium (Cd) …

Continuous globalization and industrialization have ensured metals are an increasing
aspect of daily life. Their usefulness in manufacturing has made them vital to national …

Zinc finger proteins are one of the most abundant families of proteins and present a wide
range of structures and functions. The structural zinc ion provides the correct conformation to …

Hypoxia has a significant impact on many physiological and pathological processes. Over
the recent years, its role in modulation of epigenetic remodelling has also become clearer. In …

Convincing evidence accumulated over the last decades demonstrates the crucial role of
epigenetic modifications for mammalian genome regulation and its flexibility. DNA …

Four DNA bases are essential biochemical elements for coding heritable life blueprint.
Meanwhile, organisms utilize modifying enzymes to post chemical groups on DNA bases to …

Long-term exposures to environmental toxicants are causative factors for human health
effects. DNA damages are of great interest in that they can serve as the potential biomarkers …

Exposure to heavy metals, such as cadmium, nickel, mercury, arsenic, lead, and hexavalent
chromium has been linked to dysregulated developmental processes, such as impaired …

Pollutants, such as toxic metals, negatively influence organismal health and performance,
even leading to population collapses. Studies in model organisms have shown that …

The extensive use of toxic metals in industry and agriculture leads to their wide distribution
in the environment, which raises critical concerns over their toxic effects on human health …