Highlights•Multiple, common dispersed packaging signals (PSs) promote RNA virus
assembly.•PS-mediated assembly solves a viral equivalent of Levinthal's Paradox.•RNA PSs …

The packaging of genomic RNA in positive-sense single-stranded RNA viruses is a key part
of the viral infectious cycle, yet this step is not fully understood. Unlike double-stranded DNA …

This paper is devoted to the multidisciplinary modelling of a pandemic initiated by an
aggressive virus, specifically the so-called SARS–CoV–2 Severe Acute Respiratory …

This paper focuses on the multiscale modeling of the COVID-19 pandemic and presents
further developments of the model [7] with the aim of showing how relaxations of the …

Viruses, entities composed of nucleic acids, proteins, and in some cases lipids lack the
ability to replicate outside their target cells. Their components self-assemble at the …

This paper presents a critical analysis of the literature and perspective research ideas for
modeling the epidemics caused by the SARS-CoV-2 virus. It goes beyond deterministic …

Human immunodeficiency virus (HIV) and human T-lymphotropic virus type I (HTLV-I) are
two retroviruses that attack the immune cells and impair their functions. Both HIV and HTLV-I …

The recent revolution in imaging techniques and results from RNA footprinting in situ reveal
how the bacteriophage MS2 genome regulates both particle assembly and genome release …

Alphaviruses are enveloped positive-sense RNA viruses that can cause serious human
illnesses such as polyarthritis and encephalitis. Despite their widespread distribution and …

In the literature, a great number of HIV and HTLV-I mono-infection models has been
formulated and analyzed. However, the within-host dynamics of HIV/HTLV-I co-infection has …