Immunoglobulin replacement therapy (IGRT) has contributed critically to the management of
primary antibody deficiencies (PAD) and the decrease in pneumonia rate. However, despite …

Starting about 60 years ago, a number of reports appeared that outlined the severe clinical
course of a few adult subjects with profound hypogammaglobinemia. Puzzled by the lack of …

Primary immunodeficiencies (PIDs) are inherited disorders in which one or several
components of immune system are decreased, missing, or of non-appropriate function …

Common variable immunodeficiency (CVID) refers to a grouping of antibody deficiencies
that lack a more specific genetic or phenotypic classification. It is the immunodeficiency …

Primary immunodeficiency disorders (PIDs) are caused by 1 or more defects of the immune
system. Patients are more likely to experience recurrent and/or severe infections and tend to …

Common variable immunodeficiency is a primary immunodeficiency of unknown etiology
characterized by low serum immunoglobulin G, a decreased ability to make specific …

Primary antibody deficiencies (PADs) are the most common form of primary
immunodeficiency and predispose to severe and recurrent pulmonary infections, which can …

Human primary immunodeficiency diseases (PIDs) represent a heterogeneous group of
more than 350 disorders. They are rare diseases, but their global incidence is more relevant …

Introduction Patients with common variable immunodeficiency (CVID) have a high frequency
of inflammatory complications like autoimmune cytopenias, interstitial lung disease and …

The immune system plays pivotal roles in the occurrence and progression of cancers. As
blockade of immune-checkpoint has been proven effective at improving anti-tumor immune …