Pathogenesis and treatment of Sjogren's syndrome: review and update

Q Zhan, J Zhang, Y Lin, W Chen, X Fan… - Frontiers in …, 2023 - frontiersin.org
Sjogren's syndrome (SS) is a chronic autoimmune disease accompanied by multiple
lesions. The main manifestations include dryness of the mouth and eyes, along with …

Involvement of aquaporin 5 in Sjögren's syndrome

C Chivasso, C D'Agostino, D Parisis, MS Soyfoo… - Autoimmunity …, 2023 - Elsevier
Sjögren's syndrome (SS) is a chronic autoimmune disease with the pathological hallmark of
lymphoplasmacytic infiltration of exocrine glands-more specifically salivary and lacrimal …

Dickkopf-1 as a promising therapeutic target for autoimmune diseases

SS Tao, F Cao, NB Sam, HM Li, YT Feng, J Ni… - Clinical …, 2022 - Elsevier
Abstract Dickkopf-1 (DKK-1) is mostly known as a mature inhibitor of classic Wnt signaling
pathways, which plays a critically role in regulating bone formation and bone metastasis. In …

[HTML][HTML] Differentially expressed tear proteins in Sjögren's syndrome Keratoconjunctivitis sicca

SP Yoon, Z Yu, SC Pflugfelder… - … vision science & …, 2023 - iovs.arvojournals.org
Purpose: The purpose of this study was to determine if there are significant differences in the
concentrations of tear proteins in Sjögren's syndrome keratoconjunctivitis sicca (SS KCS) …

Salivary gland tumors exhibit distinct miRNA signatures involved in Wnt/β-Catenin signaling in formalin fixed paraffin embedded tissue samples

M Koparal, E Bozgeyik, O Ceylan, B Ege… - … -Research and Practice, 2022 - Elsevier
Advances in high-throughput genomic technologies have enabled the identification of
numerous selective tumor markers. However, adapting these newly identified markers to …

A comprehensive review of Sjögren's syndrome: classification criteria, risk factors, and signaling pathways

T Zhao, R Zhang, Z Li, D Qin, X Wang - Heliyon, 2024 - cell.com
Sjögren's syndrome (SS) is a chronic autoimmune disease that affects the exocrine glands
and may lead to a range of systemic symptoms that impact various organs. Both innate and …

Primary Sjögren's syndrome: new perspectives on salivary gland epithelial cells

J Hou, Y Feng, Z Yang, Y Ding, D Cheng, Z Shi… - European Journal of …, 2024 - Springer
Primary Sjögren's syndrome (pSS) is a chronic autoimmune disease primarily affecting
exocrine glands such as the salivary glands, leading to impaired secretion and sicca …

The plasma levels of Dickkopf-1 elevated in patients with Juvenile Idiopathic Arthritis

L Ye, Y Jin, H Huang, F Ding, X Xu, C Liu, S Bao… - Pediatric …, 2023 - nature.com
Background To explore the role of two major inhibitors of Wnt signal pathway, Dickkopf-1
(DKK-1) and Sclerostin (SOST), in the pathogenesis of juvenile idiopathic arthritis (JIA) …

[PDF][PDF] Wnt 信号通路在自身免疫性疾病中的作用研究进展

徐小凡, 李一鸣, 徐小虎, 代义龙, 金呈强 - Medical Diagnosis, 2023 - pdf.hanspub.org
摘要Wnt 信号通路的异常激活与许多人类疾病的发病机制有关, 越来越多的研究表明, Wnt
信号通路的异常调控在多发性硬化症, 类风湿关节炎, 系统性红斑狼疮, 原发性干燥综合征等自身 …

The Dynamic Role of PD-1, Vitamin D, RANKL, and Sclerostin in Iraqi Patients with Systemic Lupus Erythematosus

AK Ismael, HM Alabassi - Ibn AL-Haitham Journal For Pure …, 2024 - jih.uobaghdad.edu.iq
Systemic lupus erythematosus (SLE) is a chronic, autoimmune disease, with a wide range of
clinical symptoms. Some studies have indicated the association between RANKL …