Role of reactive oxygen species in cancer progression: molecular mechanisms and recent advancements

V Aggarwal, HS Tuli, A Varol, F Thakral, MB Yerer… - Biomolecules, 2019 - mdpi.com
Reactive oxygen species (ROS) play a pivotal role in biological processes and continuous
ROS production in normal cells is controlled by the appropriate regulation between the silver …

Antimicrobial peptides as anticancer agents: functional properties and biological activities

AL Tornesello, A Borrelli, L Buonaguro, FM Buonaguro… - Molecules, 2020 - mdpi.com
Antimicrobial peptides (AMPs), or host defense peptides, are small cationic or amphipathic
molecules produced by prokaryotic and eukaryotic organisms that play a key role in the …

[HTML][HTML] Antimicrobial peptides with selective antitumor mechanisms: prospect for anticancer applications

B Deslouches, YP Di - Oncotarget, 2017 - ncbi.nlm.nih.gov
In the last several decades, there have been significant advances in anticancer therapy.
However, the development of resistance to cancer drugs and the lack of specificity related to …

Betulin and its derivatives as novel compounds with different pharmacological effects

S Amiri, S Dastghaib, M Ahmadi, P Mehrbod… - Biotechnology …, 2020 - Elsevier
Betulin (B) and Betulinic acid (BA) are natural pentacyclic lupane-structure triterpenoids
which possess a wide range of pharmacological activities. Recent evidence indicates that B …

ROS-modulated therapeutic approaches in cancer treatment

MH Raza, S Siraj, A Arshad, U Waheed… - Journal of cancer …, 2017 - Springer
Purpose Reactive oxygen species (ROS) are produced in cancer cells as a result of
increased metabolic rate, dysfunction of mitochondria, elevated cell signaling, expression of …

In Vitro Antioxidant versus Metal Ion Chelating Properties of Flavonoids: A Structure-Activity Investigation

SA Cherrak, N Mokhtari-Soulimane, F Berroukeche… - PloS one, 2016 - journals.plos.org
Natural flavonoids such as quercetin,(+) catechin and rutin as well as four methoxylated
derivatives of quercetin used as models were investigated to elucidate their impact on the …

The chemistry and biological activities of peptides from amphibian skin secretions

X Xu, R Lai - Chemical reviews, 2015 - ACS Publications
Amphibian skin is directly exposed to different environments. Amphibians interact with
environmental factors including microorganisms, parasites, predators, and physical factors …

Impact of ROS generated by chemical, physical, and plasma techniques on cancer attenuation

S Mitra, LN Nguyen, M Akter, G Park, EH Choi… - Cancers, 2019 - mdpi.com
For the last few decades, while significant improvements have been achieved in cancer
therapy, this family of diseases is still considered one of the deadliest threats to human …

Graphene quantum dots as autophagy-inducing photodynamic agents

ZM Markovic, BZ Ristic, KM Arsikin, DG Klisic… - Biomaterials, 2012 - Elsevier
The excellent photoluminescent properties of graphene quantum dots (GQD) makes them
suitable candidates for biomedical applications, but their cytotoxicity has not been …

Apoptosis and cancer: mutations within caspase genes

S Ghavami, M Hashemi, SR Ande… - Journal of medical …, 2009 - jmg.bmj.com
The inactivation of programmed cell death has profound effects not only on the development
but also on the overall integrity of multicellular organisms. Beside developmental …