The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis

K Dheda, T Gumbo, G Maartens, KE Dooley… - The lancet Respiratory …, 2017 - thelancet.com
Global tuberculosis incidence has declined marginally over the past decade, and
tuberculosis remains out of control in several parts of the world including Africa and Asia …

An update on derivatisation and repurposing of clinical nitrofuran drugs

NH Zuma, J Aucamp, DND David - European Journal of Pharmaceutical …, 2019 - Elsevier
nitrofurans (NFs) have been in clinical use for over 60 years. These affordable drugs are
used for the treatment of a broad spectrum of diseases ranging from urinary tract infections …

[HTML][HTML] Bedaquiline: Current status and future perspectives

S Khoshnood, M Goudarzi, E Taki, A Darbandi… - Journal of global …, 2021 - Elsevier
The development of drug-resistant tuberculosis (TB) is a major global threat worldwide.
Based on the World Health Organization reports, it is estimated that more than 500000 new …

[HTML][HTML] Challenges and controversies in the treatment of spinal tuberculosis

A Pandita, N Madhuripan, S Pandita… - Journal of clinical …, 2020 - Elsevier
Current guidelines regarding management of spinal TB are mostly extrapolated from trials
on pulmonary disease. Since the British Medical Research Council (BMRC) trials in the …

Effect of natural phenolics on pharmacokinetic modulation of bedaquiline in rat to assess the likelihood of potential food–drug interaction

P Kotwal, A Dogra, A Sharma, S Bhatt… - Journal of agricultural …, 2020 - ACS Publications
Bedaquiline (TMC-207) is a recently approved drug for the treatment of multidrug-resistant
tuberculosis (MDR-TB). Moreover, there is a present and growing concern for natural …

Assessment of preclinical drug interactions of bedaquiline by a highly sensitive LC-ESI-MS/MS based bioanalytical method

P Kotwal, A Magotra, A Dogra, S Sharma… - … of Chromatography B, 2019 - Elsevier
A continuous effort has been given to find out a new drug that is effective against
tuberculosis (TB) from both susceptible and resistant strains of Mycobacterium tuberculosis …

Опыт использования бедаквилина в комплексном лечении пациентов с туберкулезом, сочетанным с ВИЧ-инфекцией

ГС Баласанянц - Туберкулез и болезни легких, 2017 - tibl-journal.com
Аннотация Цель исследования: оценить эффективность и безопасность
противотуберкулезного препарата бедаквилин в комплексном лечении пациентов с …

An LC-MS/MS-based method to analyze the anti-tuberculosis drug bedaquiline in hair

J Metcalfe, R Gerona, A Wen… - … of Tuberculosis and …, 2017 - ingentaconnect.com
Bedaquiline (BDQ), a diarylquinoline demonstrating significant bactericidal and sterilizing
activity, has been approved by the US Food and Drug Administration for the treatment of …

Population implications of the use of bedaquiline in people with extensively drug-resistant tuberculosis: are fears of resistance justified?

A Kunkel, J Furin, T Cohen - The Lancet Infectious Diseases, 2017 - thelancet.com
Global rollout of the new antituberculosis drug bedaquiline has been slow, in part reflecting
concerns about spread of bedaquiline resistance. Acquired resistance to bedaquiline is …

[PDF][PDF] Assessment of knowledge and attitudes of medical students on tuberculosis

AZ Abbas, SJ Mohammed - Iraqi Postgraduate Medical Journal, 2021 - iasj.net
Assessment of Knowledge and Attitudes of Medical Students on Tuberculosis Page 1
ATTITUDES OF MEDICAL STUDENTS ON TUBERCULOSIS THE IRAQI POSTGRADUATE …