Glutathione redox imbalance in brain disorders

F Gu, V Chauhan, A Chauhan - Current Opinion in Clinical …, 2015 - journals.lww.com
GSH plays an important role during the onset and progression of neuropsychiatric and
neurodegenerative diseases. GSH redox imbalance may be a primary cause of these brain …

MicroRNAs and target genes as biomarkers for the diagnosis of early onset of Parkinson disease

AR Arshad, SA Sulaiman, AA Saperi… - Frontiers in molecular …, 2017 - frontiersin.org
Among the neurodegenerative disorders, Parkinson's disease (PD) ranks as the second
most common disorder with a higher prevalence in individuals aged over 60 years old …

Age-related neurodegenerative disease associated pathways identified in retinal and vitreous proteome from human glaucoma eyes

M Mirzaei, VB Gupta, JM Chick, TM Greco, Y Wu… - Scientific reports, 2017 - nature.com
Glaucoma is a chronic disease that shares many similarities with other neurodegenerative
disorders of the central nervous system. This study was designed to evaluate the association …

Role of Glutathione-S-transferases in neurological problems

A Kumar, DK Dhull, V Gupta, P Channana… - Expert Opinion on …, 2017 - Taylor & Francis
ABSTRACT Introduction: Role of Glutathione-S-transferases (GSTs) has been well explored
in the cellular detoxification process, regulation of redox homeostasis and S …

TNF-alpha G308A polymorphism and the susceptibility to Alzheimer's disease: an updated meta-analysis

T Wang - Archives of medical research, 2015 - Elsevier
Background and Aims Tumor necrosis factor (TNF)-alpha G308A polymorphism has been
reported in the association with susceptibility to Alzheimer's disease (AD); however, results …

Advances in understanding genomic markers and pharmacogenetics of Parkinson's disease

FJ Jiménez-Jiménez, H Alonso-Navarro… - Expert Opinion on …, 2016 - Taylor & Francis
Introduction: The inheritance pattern of Parkinson's disease (PD) is likely multifactorial
(owing to the interplay of genetic predisposition and environmental factors). Many …

The influence of ESR1 rs9340799 and ESR2 rs1256049 polymorphisms on prostate cancer risk

C Fu, WQ Dong, A Wang, G Qiu - Tumor Biology, 2014 - Springer
Abstract Estrogen receptor 1 (ESR1) and estrogen receptor 2 (ESR2) may play a role in the
development of prostate cancer. Many studies focused on ESR1 rs9340799 and ESR2 …

Glutathione S-transferase: A keystone in Parkinson's disease pathogenesis and therapy

P Padhan, N Kumar, S Verma - Molecular and Cellular Neuroscience, 2024 - Elsevier
Parkinson's disease is a progressive neurodegenerative disorder that predominantly affects
motor function due to the loss of dopaminergic neurons in the substantia nigra. It presents …

Does BDNF Val66Met polymorphism confer risk for posttraumatic stress disorder?

T Wang - Neuropsychobiology, 2015 - karger.com
Background: Evidence has indicated that BDNF (brain-derived neurotrophic factor)
Val66Met genetic variant could be linked to the development of posttraumatic stress disorder …

Association of glutathione S-transferases M1, P1 and T1 variations and risk of late-onset Alzheimer's disease

Z Jafarian, K Saliminejad, K Kamali, M Ohadi… - Neurological …, 2018 - Taylor & Francis
Abstract Objective: Late-onset Alzheimer's disease (AD) is a genetically heterogeneous
neurodegenerative disorder. Associations of the glutathione S-transferases (GSTs) …