Throughout their life, bacteria need to sense and respond to environmental stress. Thus,
such stress responses can require dramatic cellular reprogramming, both at the …

Synthesis of polyproline proteins leads to translation arrest. To overcome this ribosome
stalling effect, bacteria depend on a specialized translation elongation factor P (EF‐P), being …

Translation elongation factor P (EF-P) is critical for virulence in bacteria. EF-P is present in
all bacteria and orthologous to archaeal and eukaryotic initiation factor 5A, yet the biological …

ABSTRACT Elongation factor P (EF-P) is a universally conserved bacterial translation factor
homologous to eukaryotic/archaeal initiation factor 5A. In Salmonella, deletion of the efp …

The lysyl-tRNA synthetase paralog PoxA modifies elongation factor P (EF-P) with α-lysine at
low efficiency. Cell-free extracts containing non–α-lysine substrates of PoxA modified EF-P …

Lys34 of the conserved translation elongation factor P (EF-P) is post-translationally
lysinylated by YjeK and YjeA—a modification that is critical for bacterial virulence. Here we …

ABSTRACT Elongation factor P (EF-P) is posttranslationally modified at a conserved lysyl
residue by the coordinated action of two enzymes, PoxA and YjeK. We have previously …

ABSTRACT Elongation factor P (EF-P) is a ubiquitous bacterial protein that is required for
the synthesis of poly-proline motifs during translation. In Escherichia coli and Salmonella …

Translational control is extremely important in all organisms, and some of its aspects are
highly conserved among all primary kingdoms, such as those related to the translation …

Uropathogenic Escherichia coli (UPEC) is the cause of~ 75% of all urinary tract infections
(UTIs) and is increasingly associated with multidrug resistance. This includes UPEC strains …