Genome-scale data and the development of novel statistical phylogenetic approaches have
greatly aided the reconstruction of a broad sketch of the tree of life and resolved many of its …

Comparative genomics is the comparison of genetic information within and across
organisms to understand the evolution, structure, and function of genes, proteins, and non …

Parasitic nematodes (roundworms) and platyhelminths (flatworms) cause debilitating
chronic infections of humans and animals, decimate crop production and are a major …

Abstract The Alliance of Genome Resources (the Alliance) is a combined effort of 7
knowledgebase projects: Saccharomyces Genome Database, WormBase, FlyBase, Mouse …

Flatworms (Platyhelminthes) are a basally branching phylum that harbours a wealth of
fascinating biology, including planarians with their astonishing regenerative abilities and the …

The planarian Schmidtea mediterranea is being studied as a model species for
regeneration, but the assembly of planarian genomes remains challenging. Here, we report …

Bacterial symbioses allow annelids to colonise extreme ecological niches, such as
hydrothermal vents and whale falls. Yet, the genetic principles sustaining these symbioses …

Reconstructing the tree of life remains a central goal in biology. Early methods, which relied
on small numbers of morphological or genetic characters, often yielded conflicting …

Neuropeptides are diverse signaling molecules in animals commonly acting through G-
protein coupled receptors (GPCRs). Neuropeptides and their receptors underwent extensive …

Recent developments in sequencing technologies have greatly improved our knowledge of
phylogenetic relationships and genomic architectures throughout the tree of life. Spiralia, a …