Alzheimer's disease (AD) is a slowly progressive neurodegenerative disease conceptualized as a continuous process, ranging from mild cognitive impairment (MCI), to …
Y Yan, X Wang, D Chaput, MK Shin, Y Koh, L Gan… - Cell, 2022 - cell.com
Although women experience significantly higher tau burden and increased risk for Alzheimer's disease (AD) than men, the underlying mechanism for this vulnerability has not …
Y Liao, X Mai, X Wu, X Hu, X Luo, G Zhang - Molecules, 2022 - mdpi.com
This study investigated the inhibitory mechanism of quercetin in acetylcholinesterase (AChE) and its neuroprotective effects on β-amyloid25–35-induced oxidative stress injury in …
A Sampietro, FJ Pérez-Areales, P Martínez, EM Arce… - Pharmaceuticals, 2022 - mdpi.com
Multitarget anti-Alzheimer agents are the focus of very intensive research. Through a comprehensive bibliometric analysis of the publications in the period 1990–2020, we have …
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to dementia and patient death. AD is characterized by intracellular neurofibrillary tangles …
N Pravin, K Jozwiak - International journal of molecular sciences, 2022 - mdpi.com
Alzheimer's disease (AD) is multifactorial, progressive and the most predominant cause of cognitive impairment and dementia worldwide. The current “one-drug, one-target” approach …
A Bubley, A Erofeev, P Gorelkin… - International Journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder which is characterized by β- amyloid (Aβ) aggregation, τ-hyperphosphorylation, and loss of cholinergic neurons. The …
A Yang, C Liu, J Wu, X Kou, R Shen - European Journal of Pharmacology, 2021 - Elsevier
Alzheimer's disease (AD) is an age-related neurodegenerative disease characterized by progressive memory loss, declining language skills and other cognitive disorders. AD has …
E Suárez-González, J Sandoval-Ramírez… - Current Issues in …, 2023 - mdpi.com
Ginkgo biloba (GB) extracts have been used in clinical studies as an alternative therapy for Alzheimer's disease (AD), but the exact bioaction mechanism has not yet been elucidated. In …