Growing evidence suggests that vitamin C supplementation may be an effective adjunct
therapy in the management of people with diabetes. This paper critically reviews the current …

Background and aim It has been suggested that taking vitamin C supplements may improve
glycemic control in patients with type 2 diabetes mellitus (T2DM). However, there has not …

High-dose intravenous vitamin C (HDIVC) administered to produce pharmacologic
concentrations shows promise in preclinical models and small clinical trials, but larger …

The role of food constituents as pharmacological agents is an important consideration in
health and obesity. Vitamin C acts as a small molecule antioxidant but is also a co-factor for …

Vitamin C is an essential enzyme cofactor and antioxidant with pleiotropic roles in human
physiology. Circulating vitamin C concentrations are lower in people with diabetes mellitus …

The worldwide prevalence of type 2 diabetes (T2D) and prediabetes is rapidly increasing,
particularly in children, adolescents, and young adults. Oxidative stress (OxS) has emerged …

Vitamin C has multiple metabolic functions in the body, but the available information on the
exact relationship between these functions and the intake necessary to maintain them is …

Obesity and diabetes are known to negatively affect vitamin C status. However, whether the
presence of diabetes, in addition to obesity, contributes an additional impact on vitamin C …

Ascorbic acid, the reduced form of vitamin C, is a ubiquitous small carbohydrate. In spite of
decades of focused research, new metabolic functions of this universal electron donor are …

Background Hypovitaminosis C has negative health consequences. People with diabetes
and hypovitaminosis C may fail to conserve vitamin C in the urine, thereby displaying …