Sequencing pools of individuals—mining genome-wide polymorphism data without big funding

C Schlötterer, R Tobler, R Kofler, V Nolte - Nature Reviews Genetics, 2014 - nature.com
The analysis of polymorphism data is becoming increasingly important as a complementary
tool to classical genetic analyses. Nevertheless, despite plunging sequencing costs …

Whole‐genome sequencing approaches for conservation biology: Advantages, limitations and practical recommendations

AP Fuentes‐Pardo, DE Ruzzante - Molecular ecology, 2017 - Wiley Online Library
Whole‐genome resequencing (WGR) is a powerful method for addressing fundamental
evolutionary biology questions that have not been fully resolved using traditional methods …

Extreme genomic erosion after recurrent demographic bottlenecks in the highly endangered Iberian lynx

F Abascal, A Corvelo, F Cruz, JL Villanueva-Cañas… - Genome biology, 2016 - Springer
Background Genomic studies of endangered species provide insights into their evolution
and demographic history, reveal patterns of genomic erosion that might limit their viability …

SNPGenie: estimating evolutionary parameters to detect natural selection using pooled next-generation sequencing data

CW Nelson, LH Moncla, AL Hughes - Bioinformatics, 2015 - academic.oup.com
New applications of next-generation sequencing technologies use pools of DNA from
multiple individuals to estimate population genetic parameters. However, no publicly …

A flexible multi‐species genome‐wide 60K SNP chip developed from pooled resequencing of 240 Eucalyptus tree genomes across 12 species

OB Silva‐Junior, DA Faria, D Grattapaglia - New Phytologist, 2015 - Wiley Online Library
We used whole genome resequencing of pooled individuals to develop a high‐density
single‐nucleotide polymorphism (SNP) chip for Eucalyptus. Genomes of 240 trees of 12 …

Population genomics from pool sequencing

L Ferretti, SE Ramos‐Onsins… - Molecular …, 2013 - Wiley Online Library
Next generation sequencing of pooled samples is an effective approach for studies of
variability and differentiation in populations. In this paper we provide a comprehensive set of …

Drosophila Evolution over Space and Time (DEST): A New Population Genomics Resource

M Kapun, JCB Nunez… - Molecular biology …, 2021 - academic.oup.com
Drosophila melanogaster is a leading model in population genetics and genomics, and a
growing number of whole-genome data sets from natural populations of this species have …

Single Geographic Origin of a Widespread Autotetraploid Arabidopsis arenosa Lineage Followed by Interploidy Admixture

B Arnold, ST Kim, K Bomblies - Molecular biology and evolution, 2015 - academic.oup.com
Whole-genome duplication, which leads to polyploidy, has been implicated in speciation
and biological novelty. In plants, many species exhibit ploidy variation, which is likely …

Climate‐specific biosynthetic gene clusters in populations of a lichen‐forming fungus

G Singh, A Calchera, M Schulz… - Environmental …, 2021 - Wiley Online Library
Natural products can contribute to abiotic stress tolerance in plants and fungi. We
hypothesize that biosynthetic gene clusters (BGCs), the genomic elements that underlie …

Intra-species differences in population size shape life history and genome evolution

D Willemsen, R Cui, M Reichard, DR Valenzano - Elife, 2020 - elifesciences.org
The evolutionary forces shaping life history divergence within species are largely unknown.
Turquoise killifish display differences in lifespan among wild populations, representing an …