Major depressive disorder (MDD) is characterized by persistent depressed mood, loss of
interest or pleasure in previously enjoyable activities, recurrent thoughts of death, and …

The growing interest in the rapid and sustained antidepressant effects of the dissociative
anesthetic ketamine and classic psychedelics, such as psilocybin, is remarkable. However …

Ketamine has emerged as a transformative and mechanistically novel pharmacotherapy for
depression. Its rapid onset of action, efficacy for treatment-resistant symptoms, and …

Cervical spinal cord injury (SCI) leads to permanent impairment of arm and hand functions.
Here we conducted a prospective, single-arm, multicenter, open-label, non-significant risk …

Importance Electroconvulsive therapy (ECT) is highly effective and rapid in treating
depression, but it carries a risk of significant cognitive adverse effects. Magnetic seizure …

Many drugs used in medicine have on-and off-label indications that span different medical
disciplines. Ketamine now has evidence of efficacy for emergency …

Ketamine offers promising new therapeutic options for difficult-to-treat depression. The
efficacy of treatment response, including ketamine, has been intricately linked to EEG …

This Viewpoint examines key issues stemming from severalrecentreportsofelectroconvulsivether…
(ECT) vs ketamine infusion for improving depressive symptoms in treatment-resistant …

Chronic pain is a frequent, distressing and poorly understood health problem. Plasticity of
synaptic transmission in the nociceptive pathways after inflammation or injury is assumed to …

Background Subanesthetic ketamine has accumulated meta-analytic evidence for rapid
antidepressant effects in treatment-resistant depression (TRD), resulting in both excitement …