Cell migration requires sustained forward movement of the plasma membrane at the cell's
front or" leading edge." To date, researchers have uncovered four distinct ways of extending …

Adenosine triphosphate (ATP) is a central metabolite that plays an indispensable role in
various cellular processes, from energy supply to cell‐to‐cell signaling. Nature has …

The introduction of high-resolution time lapse imaging and molecular biological tools has
changed dramatically the rate of progress towards the understanding of the complex …

Dendritic spines are small actin-rich protrusions from neuronal dendrites that form the
postsynaptic part of most excitatory synapses and are major sites of information processing …

Axon outgrowth and guidance to the proper target requires the coordination of filamentous
(F)-actin and microtubules (MTs), the dynamic cytoskeletal polymers that promote shape …

Memory, defined as the storage and use of learned information in the brain, is necessary to
modulate behavior and critical for animals to adapt to their environments and survive …

Actin remodeling is at the heart of the response of cells to external or internal stimuli,
allowing a variety of membrane protrusions to form. Fifteen years ago, tunneling nanotubes …

The correct subcellular distribution of proteins establishes the complex morphology and
function of neurons. Fluorescence microscopy techniques are invaluable to investigate …

Excitatory synapses in the brain play key roles in learning and memory. The formation and
functions of postsynaptic mushroom-shaped structures, dendritic spines, and possibly of …

Posttranscriptional gene expression including splicing, RNA transport, translation, and RNA
decay provides an important regulatory layer in many if not all molecular pathways …