Antibiotics are the commonest cause of life-threatening immune-mediated drug reactions
that are considered off-target, including anaphylaxis, and organ-specific and severe …

Vaccination continues to be the single most important and successful public health
intervention, due to its prevention of morbidity and mortality from prevalent infectious …

Precision medicine promises improved health by accounting for individual variability in
genes, environment, and lifestyle. Precision medicine will continue to transform healthcare …

Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic
symptoms (DIHS/DRESS) is one example of a severe delayed T-cell–mediated adverse …

Controversies exist with regard to in vivo approaches to delayed immunologically mediated
adverse drug reactions, such as exanthem (maculopapular eruption), drug reaction with …

Symptoms) is a complex multisystemic severe drug hypersensitivity reaction whose
diagnosis and management are troublesome. It involves the management by different …

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening
diseases characterized by detachment of the epidermis and mucous membrane. SJS/TEN …

Cutaneous adverse drug reactions are unpredictable and include various different skin
conditions of varying degrees of severity. The most concerning are usually referred to as …

In the manuscript, a strong recommendation is indicated by the phrase “we recommend” and
a conditional or weakened recommendation is indicated by “we suggest”. An open …

British Association of Dermatologists' guidelines for the management of Stevens–Johnson
syndrome/toxic epidermal necrolysis in children and young people, 2018 | British Journal of …