After three decades of developments, single particle tracking (SPT) has become a powerful
tool to interrogate dynamics in a range of materials including live cells and novel catalytic …

Skeletal muscle regeneration is a finely tuned process involving the activation of various
cellular and molecular processes. Satellite cells, the stem cells of skeletal muscle, are …

Simple Summary The cytoskeleton is a network of protein fibres within cells that provide
structure and support intracellular transport. Focal adhesions are protein complexes …

Cell-directed changes in the ligand-binding affinity ('activation') of integrins regulate cell
adhesion and migration, extracellular matrix assembly and mechanotransduction, thereby …

Advances in molecular biology, organic chemistry, and materials science have recently
created several new classes of fluorescent probes for imaging in cell biology. Here we …

Mechanical stimuli profoundly alter cell fate, yet the mechanisms underlying
mechanotransduction remain obscure because of a lack of methods for molecular force …

Directed cell migration is a physical process that requires dramatic changes in cell shape
and adhesion to the extracellular matrix. For efficient movement, these processes must be …

Focal adhesions undergo myosin-II-mediated maturation wherein they grow and change
composition to modulate integrin signalling for cell migration, growth and differentiation. To …

Integrin adhesion complexes (IACs) are integrin-based plasma-membrane-associated
compartments where cells sense environmental cues. The physical mechanisms and …

Membrane lateral heterogeneity is accepted as a requirement for the function of biological
membranes and the notion of lipid rafts gives specificity to this broad concept. However, the …