Demystifying emerging bulk RNA-Seq applications: the application and utility of bioinformatic methodology

AS Thind, I Monga, PK Thakur, P Kumari… - Briefings in …, 2021 - academic.oup.com
Significant innovations in next-generation sequencing techniques and bioinformatics tools
have impacted our appreciation and understanding of RNA. Practical RNA sequencing …

Bridging tumorigenesis and therapy resistance with a non-darwinian and non-lamarckian mechanism of adaptive evolution

F Catania, B Ujvari, B Roche, JP Capp… - Frontiers in …, 2021 - frontiersin.org
Although neo-Darwinian (and less often Lamarckian) dynamics are regularly invoked to
interpret cancer's multifarious molecular profiles, they shine little light on how tumorigenesis …

One Cell, Two Gears: Extensive Somatic Genome Plasticity Accompanies High Germline Genome Stability in Paramecium

F Catania, R Rothering, V Vitali - Genome Biology and Evolution, 2021 - academic.oup.com
Mutation accumulation (MA) experiments are conventionally employed to study
spontaneous germline mutations. However, MA experiments can also shed light on somatic …

Cross-Generational Effects and Non-random Developmental Response to Temperature Variation in Paramecium

R Hagen, V Vitali, F Catania - Frontiers in Cell and Developmental …, 2020 - frontiersin.org
Unicellular organisms such as ciliates are largely neglected in research on adaptive
developmental plasticity, although their nuclear dualism offers ideal circumstances to study …

The Mediating Role of IDL Particles in the Relationship between Primary Hypertension and Cardiovascular Diseases: Insights from Mendelian Randomization and …

Y Liu, H Wu, H Lv, Y Zhou - 2024 - researchsquare.com
Background Primary hypertension is a major risk factor for various cardiovascular diseases.
Although low-density lipoprotein and high-density lipoprotein are known to influence …

Highlight: Sex As Stress Management in Microbes

C McGrath - 2020 - academic.oup.com
Why is sex so popular? The question of why so many organisms reproduce sexually has
mystified evolutionary biologists since before Darwin, who wrote that “The whole subject is …