[HTML][HTML] Effects of chemotherapeutic agents on male germ cells and possible ameliorating impact of antioxidants

S Ghafouri-Fard, H Shoorei, A Abak, M Seify… - Biomedicine & …, 2021 - Elsevier
Abstract Treatment of cancer in young adults is associated with several side effects,
particularly in the reproductive system. Detrimental effects of chemotherapy on the germ …

Immunomodulatory effects of selenium‐enriched peptides from soybean in cyclophosphamide‐induced immunosuppressed mice

J Zhang, S Gao, H Li, M Cao, W Li… - Food science & …, 2021 - Wiley Online Library
In this study, selenium‐enriched soybean peptides (< 3 kDa, named Se‐SPep) was isolated
and purified from the selenium‐enriched soybean protein (Se‐SPro) hydrolysate by …

Modulatory effect of amifostine (WR-1065) against genotoxicity and oxidative stress induced by methotrexate in human umbilical vein endothelial cells (HUVECs)

S Aghajanshakeri, A Salmanmahiny… - Toxicology …, 2023 - Taylor & Francis
Amifostine is used in chemotherapy and radiotherapy as a cytoprotective adjuvant alongside
DNA-binding chemotherapeutic agents. It functions by reducing free radicals and detoxifying …

Phellinus baumii enhances the immune response in cyclophosphamide-induced immunosuppressed mice

JH Yoo, YS Lee, SK Ku, HJ Lee - Nutrition research, 2020 - Elsevier
Phellinus species is a mushroom used as traditional medicine in Eastern Asia. Research on
Phellinus baumii (PB) is relatively limited; however, it has been reported to have antioxidant …

Frankincense extract protects against testicular damage through augmentation of antioxidant defense mechanisms and modulation of apoptotic genes expression

SA Alharbi, M Asad, KEA Abdelsalam, S Chandy… - Scientific Reports, 2022 - nature.com
Abstract Frankincense (Boswellia sacra Fluck.,) is traditionally used in the treatment of
altered male fertile potential in several countries. This study evaluated the cytoprotective …

Counteractive effects of extracts of Mangifera indica on testes of Wistar Rat exposed to cyclophosphamide

OS Ayegbusi, LA Enye, OS Saka, AO Omoaghe - Heliyon, 2023 - cell.com
Introduction Infertility may have a variety of causes that can affect both the male and female
reproductive systems. Cyclophosphamide is a drug used in chemotherapy and immune …

The role of amifostine in preventing radiotherapy induced testicular tissue damage in rats

A Gezer, E Karadag-Sari - Biotechnic & Histochemistry, 2022 - Taylor & Francis
The germinal epithelium of the adult testis is susceptible to radiation induced damage.
Amifostine is a drug used to prevent the side effects of radiotherapy (RT) and chemotherapy …

Hepatoprotective effect of amifostine and WR-1065 on acetaminophen-induced liver toxicity on Wistar rats

H Rasouli, BM Razavi… - Naunyn-Schmiedeberg's …, 2024 - Springer
Purpose The most important problem with acetaminophen is its hepatotoxicity. N-
acetylcysteine (NAC) is used to treat the hepatotoxicity of acetaminophen. Due to the …

[HTML][HTML] Preventive effects of quercetin against inflammation and apoptosis in cyclophosphamide-induced testicular damage

D Uzun-Goren, YH Uz - Iranian Journal of Basic Medical Sciences, 2024 - ncbi.nlm.nih.gov
Objective (s): We aimed to investigate the effects of quercetin (QRC) against
cyclophosphamide (CP)-induced testicular damage and how it interacts with apoptotic and …

Morin-5′-Sulfonic acid sodium salt (NaMSA) attenuates cyclophosphamide-induced histological changes in genitourinary tract in rats

A Merwid-Ląd, D Ksiądzyna, A Hałoń, D Szkudlarek… - Pharmaceuticals, 2021 - mdpi.com
Cyclophosphamide (CPX) exerts toxicity in the urogenital system. The current study was
designed to evaluate the effect of morin-5′-sulfonic acid sodium salt (NaMSA) on CPX …