The treatment of long-gap (> 10 mm) peripheral nerve injury (PNI) and spinal cord injury
(SCI) remains a continuous challenge due to limited native tissue regeneration capabilities …

Because of the complex nerve anatomy and limited regeneration ability of natural tissue, the
current treatment effect for long-distance peripheral nerve regeneration and spinal cord …

Rhythm generating neurons are thought to be ipsilaterally-projecting excitatory neurons in
the thoracolumbar mammalian spinal cord. Recently, a subset of Shox2 interneurons (Shox2 …

Motoneurons are traditionally viewed as the output of the spinal cord that do not influence
locomotor rhythmogenesis. We assessed the role of motoneuron firing during ongoing …

In the mouse spinal cord, V1 interneurons are a heterogeneous population of inhibitory
spinal interneurons that have been implicated in regulating the frequency of the locomotor …

Physiological responses to nociceptive stimuli are initiated within tens of milliseconds, but
the corresponding sub-second behavioral responses have not been adequately explored in …

In the spinal cord, classes of interneurons have been studied in vitro to determine their role
in producing or regulating locomotion. It is unclear whether all locomotor behaviors are …

This article aims to review studies that have investigated the role of neurons that use the
transmitter acetylcholine (ACh) in controlling the operation of locomotor neural networks …

The most evident phenotype of degenerative motoneuron disease is the loss of motor
function which accompanies motoneuron death. In both amyotrophic lateral sclerosis (ALS) …

We describe and analyze a computational model of neural circuits in the mammalian spinal
cord responsible for generating and shaping locomotor-like oscillations. The model …