In silico labeling in cell biology: Potential and limitations

N Elmalam, LB Nedava, A Zaritsky - Current Opinion in Cell Biology, 2024 - Elsevier
In silico labeling is the computational cross-modality image translation where the output
modality is a subcellular marker that is not specifically encoded in the input image, for …

Image denoising and the generative accumulation of photons

A Krull, H Basevi, B Salmon, A Zeug… - Proceedings of the …, 2024 - openaccess.thecvf.com
We present a fresh perspective on shot noise corrupted images and noise removal. By
viewing image formation as the sequential accumulation of photons on a detector grid, we …

Can virtual staining for high-throughput screening generalize?

S Tonks, C Nguyen, S Hood, R Musso… - arXiv preprint arXiv …, 2024 - arxiv.org
The large volume and variety of imaging data from high-throughput screening (HTS) in the
pharmaceutical industry present an excellent resource for training virtual staining models …

Seeing more with less: Extensible Immunofluorescence (ExIF) accessibly generates high-plexity datasets by integrating standard 4-plex imaging data

J Lock, I Gunawan, F Kohane, K Nguyen, Y Zheng… - 2024 - researchsquare.com
Standard immunofluorescence imaging captures just~ 4 molecular markers ('4-plex') per
cell, limiting dissection of complex biology. Inspired by multimodal omics-based data …