Candida is the most implicated fungal pathogen in the clinical setting. Several factors play
important roles in the pathogenesis of Candida spp. Multiple transcriptional circuits …

Candida albicans has remained the main etiological agent of candidiasis, challenges
clinicians with high mortality and morbidity. The emergence of resistance to antifungal drugs …

Fungal infections, especially infections caused by Candida albicans, remain a challenging
problem in clinical settings. Despite the development of more-effective antifungal drugs, their …

The inhibition of recombinant CpLIP2 lipase/acyltransferase from Candida parapsiolosis
was considered a key model for novel antifungal drug discovery and a potential therapeutic …

To investigate some virulence factors in Candida species isolated from patients with
suspected invasive fungal infection and to identify their relationship with Candida …

The present study aims to investigate the relationship between in silico experimental data
and in vitro inhibitory data of polyphenols against α-glucosidase. The CDOCKER protocol in …

Pancreatic lipase (PL) is a primary lipase critical for triacylglyceride digestion in humans and
is considered as a promising target for the treatment of obesity. Although the current …

The superoxide radical ion is involved in numerous physiological processes, associated
with both health and pathology. Its participation in cancer onset and progression is well …

Background Over-consumption of foods high in purines like seafood, red meat, and
alcoholic beverages leads to hyperuricemia causing gout attacks. Xanthine oxidase was …

Tetrahydrolipstatin (THL), its enantiomer, and an additional six diastereomers were
evaluated as inhibitors of the hydrolysis of p-nitrophenyl butyrate by porcine pancreatic …