What can we learn from inactivation studies? Lessons from auditory cortex

ZA Slonina, KC Poole, JK Bizley - Trends in Neurosciences, 2022 - cell.com
Inactivation experiments in auditory cortex (AC) produce widely varying results that
complicate interpretations regarding the precise role of AC in auditory perception and …

[HTML][HTML] Integration of visual information in auditory cortex promotes auditory scene analysis through multisensory binding

H Atilgan, SM Town, KC Wood, GP Jones, RK Maddox… - Neuron, 2018 - cell.com
How and where in the brain audio-visual signals are bound to create multimodal objects
remains unknown. One hypothesis is that temporal coherence between dynamic …

[HTML][HTML] Ferret contributions to the business of sensory neurobiology

RHC Norris, JK Bizley - Current Opinion in Neurobiology, 2024 - Elsevier
In this brief review, we will highlight the ferret Mustela putorius furo as an increasingly
utilized animal model for sensory systems and cognitive neuroscience research. In …

Egocentric and allocentric representations in auditory cortex

SM Town, WO Brimijoin, JK Bizley - PLoS biology, 2017 - journals.plos.org
A key function of the brain is to provide a stable representation of an object's location in the
world. In hearing, sound azimuth and elevation are encoded by neurons throughout the …

Sound identity is represented robustly in auditory cortex during perceptual constancy

SM Town, KC Wood, JK Bizley - Nature communications, 2018 - nature.com
Perceptual constancy requires neural representations that are selective for object identity,
but also tolerant across identity-preserving transformations. How such representations arise …

Neurons in primary auditory cortex represent sound source location in a cue-invariant manner

KC Wood, SM Town, JK Bizley - Nature Communications, 2019 - nature.com
Auditory cortex is required for sound localisation, but how neural firing in auditory cortex
underlies our perception of sound sources in space remains unclear. Specifically, whether …

Corticofugal modulation of temporal and rate representations in the inferior colliculus of the awake marmoset

X Wang, Y Zhang, S Bai, R Qi, H Sun, R Li… - Cerebral …, 2022 - academic.oup.com
Temporal processing is crucial for auditory perception and cognition, especially for
communication sounds. Previous studies have shown that the auditory cortex and the …

Selective corticofugal modulation on sound processing in auditory thalamus of awake marmosets

X Wang, Y Zhang, L Zhu, S Bai, R Li, H Sun… - Cerebral …, 2023 - academic.oup.com
Cortical feedback has long been considered crucial for the modulation of sensory perception
and recognition. However, previous studies have shown varying modulatory effects of the …

Reversible Inactivation of Ferret Auditory Cortex Impairs Spatial and Nonspatial Hearing

SM Town, KC Poole, KC Wood… - Journal of …, 2023 - Soc Neuroscience
A key question in auditory neuroscience is to what extent are brain regions functionally
specialized for processing specific sound features, such as location and identity. In auditory …

Reversal of age-related changes in cortical sound-azimuth selectivity with training

Y Cheng, Y Zhang, F Wang, G Jia, J Zhou… - Cerebral …, 2020 - academic.oup.com
The compromised abilities to understand speech and localize sounds are two hallmark
deficits in aged individuals. Earlier studies have shown that age-related deficits in cortical …