DNA virus replication compartments
M Schmid, T Speiseder, T Dobner… - Journal of virology, 2014 - Am Soc Microbiol
Viruses employ a variety of strategies to usurp and control cellular activities through the
orchestrated recruitment of macromolecules to specific cytoplasmic or nuclear …
orchestrated recruitment of macromolecules to specific cytoplasmic or nuclear …
Crosstalk between nucleocytoplasmic trafficking and the innate immune response to viral infection
The nuclear pore complex is the sole gateway connecting the nucleoplasm and cytoplasm.
In humans, the nuclear pore complex is one of the largest multiprotein assemblies in the cell …
In humans, the nuclear pore complex is one of the largest multiprotein assemblies in the cell …
Imaging the adenovirus infection cycle
N Pied, H Wodrich - FEBS letters, 2019 - Wiley Online Library
Incoming adenoviruses seize control of cytosolic transport mechanisms to relocate their
genome from the cell periphery to specialized sites in the nucleoplasm. The nucleus is the …
genome from the cell periphery to specialized sites in the nucleoplasm. The nucleus is the …
Viral subversion of the nuclear pore complex
V Le Sage, AJ Mouland - Viruses, 2013 - mdpi.com
The nuclear pore complex (NPC) acts as a selective barrier between the nucleus and the
cytoplasm and is responsible for mediating communication by regulating the transport of …
cytoplasm and is responsible for mediating communication by regulating the transport of …
ValidNESs: a database of validated leucine-rich nuclear export signals
Abstract ValidNESs (http://validness. ym. edu. tw/) is a new database for experimentally
validated leucine-rich nuclear export signal (NES)-containing proteins. The therapeutic …
validated leucine-rich nuclear export signal (NES)-containing proteins. The therapeutic …
Identification of inhibitors and drug targets for human adenovirus infections
M Liu, L Jiang, W Cao, J Wu, X Chen - Viruses, 2022 - mdpi.com
Adenoviruses can cause infections in people of all ages at all seasons of the year.
Adenovirus infections cause mild to severe illnesses. Children, immunocompromised …
Adenovirus infections cause mild to severe illnesses. Children, immunocompromised …
The Cajal body protein p80-coilin forms a complex with the adenovirus L4-22K protein and facilitates the nuclear export of adenovirus mRNA
Cajal bodies (CBs) are major sub-nuclear structures in most eucaryotic cells. In human
adenovirus 5 (Ad5) infection, CBs are reorganized into microfoci in the late phase of …
adenovirus 5 (Ad5) infection, CBs are reorganized into microfoci in the late phase of …
In vitro toxicity and efficacy of verdinexor, an exportin 1 inhibitor, on opportunistic viruses affecting immunocompromised individuals
DG Widman, S Gornisiewicz, S Shacham, S Tamir - PloS one, 2018 - journals.plos.org
Infection of immunocompromised individuals with normally benign opportunistic viruses is a
major health burden globally. Infections with viruses such as Epstein-Barr virus (EBV) …
major health burden globally. Infections with viruses such as Epstein-Barr virus (EBV) …
Emerging from the unknown: structural and functional features of agnoprotein of polyomaviruses
AS Saribas, P Coric, A Hamazaspyan… - Journal of cellular …, 2016 - Wiley Online Library
Agnoprotein is an important regulatory protein of polyomaviruses, including JCV, BKV, and
SV40. In the absence of its expression, these viruses are unable to sustain their productive …
SV40. In the absence of its expression, these viruses are unable to sustain their productive …
Nuclear export of human hepatitis B virus core protein and pregenomic RNA depends on the cellular NXF1-p15 machinery
Hepatitis B virus (HBV) core protein (HBc) can shuttle between nucleus and cytoplasm.
Cytoplasm-predominant HBc is clinically associated with severe liver inflammation …
Cytoplasm-predominant HBc is clinically associated with severe liver inflammation …