Protein cage assembly across multiple length scales

WM Aumiller, M Uchida, T Douglas - Chemical Society Reviews, 2018 - pubs.rsc.org
Within the materials science community, proteins with cage-like architectures are being
developed as versatile nanoscale platforms for use in protein nanotechnology. Much effort …

The amazing HK97 fold: versatile results of modest differences

RL Duda, CM Teschke - Current opinion in virology, 2019 - Elsevier
Highlights•Mature capsid size and shape are determined during the assembly of
procapsids.•Intra-capsomer and inter-capsomer contacts are critical for regulating procapsid …

Metal-directed, chemically tunable assembly of one-, two-and three-dimensional crystalline protein arrays

JD Brodin, XI Ambroggio, C Tang, KN Parent… - Nature …, 2012 - nature.com
Proteins represent the most sophisticated building blocks available to an organism and to
the laboratory chemist. Yet, in contrast to nearly all other types of molecular building blocks …

Organization of the influenza virus replication machinery

A Moeller, RN Kirchdoerfer, CS Potter, B Carragher… - Science, 2012 - science.org
Influenza virus ribonucleoprotein complexes (RNPs) are central to the viral life cycle and in
adaptation to new host species. RNPs are composed of the viral genome, viral polymerase …

Principles of virus structural organization

BVV Prasad, MF Schmid - Viral Molecular Machines, 2012 - Springer
Viruses, the molecular nanomachines infecting hosts ranging from prokaryotes to
eukaryotes, come in different sizes, shapes, and symmetries. Questions such as what …

An intron endonuclease facilitates interference competition between coinfecting viruses

EA Birkholz, CJ Morgan, TG Laughlin, RK Lau… - Science, 2024 - science.org
Introns containing homing endonucleases are widespread in nature and have long been
assumed to be selfish elements that provide no benefit to the host organism. These genetic …

[HTML][HTML] Nature׳ s favorite building block: Deciphering folding and capsid assembly of proteins with the HK97-fold

MM Suhanovsky, CM Teschke - Virology, 2015 - Elsevier
For many (if not all) bacterial and archaeal tailed viruses and eukaryotic Herpesvirdae the
HK97-fold serves as the major architectural element in icosahedral capsid formation while …

Virus removal and inactivation in a hybrid microfiltration–UV process with a photocatalytic membrane

B Guo, EV Pasco, I Xagoraraki, VV Tarabara - Separation and Purification …, 2015 - Elsevier
The study describes the first application of photocatalytic membranes for virus removal and
inactivation. In the proposed hybrid treatment process, a UV lamp and a microfiltration …

[HTML][HTML] Structure of the Borrelia Bacteriophage φBB1 Procapsid

J Rūmnieks, T Füzik, K Tārs - Journal of Molecular Biology, 2023 - Elsevier
Bacteriophages of Borrelia burgdorferi are a biologically important but under-investigated
feature of the Lyme disease-causing spirochete. No virulent borrelial viruses have been …

Acquiring structural information on virus particles with charge detection mass spectrometry

DZ Keifer, T Motwani, CM Teschke… - Journal of the American …, 2016 - ACS Publications
Charge detection mass spectrometry (CDMS) is a single-molecule technique particularly
well-suited to measuring the mass and charge distributions of heterogeneous, MDa-sized …