Roles of transposable elements in the regulation of mammalian transcription

R Fueyo, J Judd, C Feschotte, J Wysocka - Nature reviews Molecular …, 2022 - nature.com
Transposable elements (TEs) comprise about half of the mammalian genome. TEs often
contain sequences capable of recruiting the host transcription machinery, which they use to …

Transposable elements shape the evolution of mammalian development

AD Senft, TS Macfarlan - Nature Reviews Genetics, 2021 - nature.com
Transposable elements (TEs) promote genetic innovation but also threaten genome stability.
Despite multiple layers of host defence, TEs actively shape mammalian-specific …

Transposable elements in mammalian chromatin organization

HA Lawson, Y Liang, T Wang - Nature Reviews Genetics, 2023 - nature.com
Transposable elements (TEs) are mobile DNA elements that comprise almost 50% of
mammalian genomic sequence. TEs are capable of making additional copies of themselves …

Regulatory activities of transposable elements: from conflicts to benefits

EB Chuong, NC Elde, C Feschotte - Nature Reviews Genetics, 2017 - nature.com
Transposable elements (TEs) are a prolific source of tightly regulated, biochemically active
non-coding elements, such as transcription factor-binding sites and non-coding RNAs. Many …

Transposable elements as essential elements in the control of gene expression

A Gebrie - Mobile DNA, 2023 - Springer
Interspersed repetitions called transposable elements (TEs), commonly referred to as mobile
elements, make up a significant portion of the genomes of higher animals. TEs contribute in …

Mammalian transposable elements and their impacts on genome evolution

RN Platt, MW Vandewege, DA Ray - Chromosome Research, 2018 - Springer
Transposable elements (TEs) are genetic elements with the ability to mobilize and replicate
themselves in a genome. Mammalian genomes are dominated by TEs, which can reach …

A mouse-specific retrotransposon drives a conserved Cdk2ap1 isoform essential for development

AJ Modzelewski, W Shao, J Chen, A Lee, X Qi, M Noon… - Cell, 2021 - cell.com
Retrotransposons mediate gene regulation in important developmental and pathological
processes. Here, we characterized the transient retrotransposon induction during …

Evolution and diversity of transposable elements in fish genomes

F Shao, M Han, Z Peng - Scientific reports, 2019 - nature.com
Transposable elements (TEs) are genomic sequences that can move, multiply, and often
form sizable fractions of vertebrate genomes. Fish belong to a unique group of vertebrates …

Long terminal repeats power evolution of genes and gene expression programs in mammalian oocytes and zygotes

V Franke, S Ganesh, R Karlic, R Malik… - Genome …, 2017 - genome.cshlp.org
Retrotransposons are “copy-and-paste” insertional mutagens that substantially contribute to
mammalian genome content. Retrotransposons often carry long terminal repeats (LTRs) for …

Genetics and signaling mechanisms of orofacial clefts

K Reynolds, S Zhang, B Sun, MA Garland… - Birth defects …, 2020 - Wiley Online Library
Craniofacial development involves several complex tissue movements including several
fusion processes to form the frontonasal and maxillary structures, including the upper lip and …