Inflammation is the primary response to infection and injury. Its beneficial effect is an
immediate resolution of the pathophysiological event. However, sustained production of …

Anticancer chemotherapy (ACT) remains a cornerstone in cancer treatment, despite
significant advances in pharmacology over recent decades. However, its associated side …

Oxidative stress is one of the most important factors in changing bone homeostasis. Redox
homeostasis plays a key role in the osteogenic differentiation of bone mesenchymal stem …

Psoriasis is a chronic inflammatory skin disorder characterized by abnormal keratinocytes
proliferation and multiple immune cells infiltration in the dermis and epidermis. Although …

Ethnopharmacological relevance Mangifera indica (family Anacardiaceae), often
acknowledged as mango and renowned for being a plant of diverse ethnopharmacological …

Context: The overproduction of reactive oxygen species (ROS) during in vitro culture of ovar-
ian tissues impairs follicular development and survival. Aims: To evaluate the effects of …

Experimental animal models are crucial for elucidating the pathophysiology of liver injuries
and for assessing new hepatoprotective agents. Drugs and chemicals such as …

This study examines Dabigatran's (Dab) capacity to mitigate methotrexate (MTX)-induced
coagulation disorders and endothelial dysfunction, while exploring its effects on oxidative …

This work aimed to investigate a possible mechanism that may mediate the hepatoprotective
effects of pomegranate fruit extract (PFE) against thioacetamide (THIO)-induced liver fibrosis …

Hepatotoxicity is the main off-target effect of methotrexate (MTX) limiting its effective clinical
use. Besides, MDA-MB231 breast cancer cells show chemoresistance, partly via PI3K/AKT …