Common and novel markers for measuring inflammation and oxidative stress ex vivo in research and clinical practice—which to use regarding disease outcomes?
Many chronic conditions such as cancer, chronic obstructive pulmonary disease, type-2
diabetes, obesity, peripheral/coronary artery disease and auto-immune diseases are …
diabetes, obesity, peripheral/coronary artery disease and auto-immune diseases are …
Epigenetic regulation of papillary thyroid carcinoma by long non-coding RNAs
RX Lin, SL Yang, Y Jia, JC Wu, Z Xu… - Seminars in Cancer …, 2022 - Elsevier
Thyroid cancer is the most common primary endocrine malignancy with papillary thyroid
carcinoma (PTC) its most common subtype. The jump in diagnoses over last many years has …
carcinoma (PTC) its most common subtype. The jump in diagnoses over last many years has …
DEAD-box RNA helicase protein DDX21 as a prognosis marker for early stage colorectal cancer with microsatellite instability
A Tanaka, JY Wang, J Shia, Y Zhou, M Ogawa… - Scientific reports, 2020 - nature.com
Abstract DEAD-box RNA helicase DDX21 (also named nucleolar RNA helicase 2) is a
nuclear autoantigen with undefined roles in cancer. To explore possible roles of …
nuclear autoantigen with undefined roles in cancer. To explore possible roles of …
RNA-interference-mediated miR-122-based gene regulation in colon cancer, a structural in silico analysis
H Ganesan, SK Nandy, A Banerjee, S Pathak… - International Journal of …, 2022 - mdpi.com
The role of microRNA 122 (miR-122) in colorectal cancer (CRC) has not been widely
investigated. In the current study, we aimed to identify the prominent gene and protein …
investigated. In the current study, we aimed to identify the prominent gene and protein …
Transcription regulation and genome rewiring governing sensitivity and resistance to FOXM1 inhibition in breast cancer
Y Ziegler, VS Guillen, SH Kim, JA Katzenellenbogen… - Cancers, 2021 - mdpi.com
Simple Summary The oncogenic transcription factor FOXM1 is overexpressed in many
cancers and associated with poor patient outcomes. Hence, there is much interest in …
cancers and associated with poor patient outcomes. Hence, there is much interest in …
Proteomic basis for pancreatic acinar cell carcinoma and pancreatoblastoma as similar yet distinct entities
A Tanaka, M Ogawa, Y Zhou, RC Hendrickson… - NPJ Precision …, 2024 - nature.com
Acinar cell carcinoma (ACC) and pancreatoblastoma (PBL) are rare pancreatic
malignancies with acinar differentiation. Proteogenomic profiling of ACC and PBL revealed …
malignancies with acinar differentiation. Proteogenomic profiling of ACC and PBL revealed …
Targeting STAT proteins via computational analysis in colorectal cancer
Colorectal cancer (CRC) is the third most common cancer diagnosed worldwide making it a
serious global challenge. CRC progression results from dysregulated cytoplasmic …
serious global challenge. CRC progression results from dysregulated cytoplasmic …
Clinical and molecular assessment of an onco‐immune signature with prognostic significance in patients with colorectal cancer
Understanding the complex tumor microenvironment is key to the development of
personalized therapies for the treatment of cancer including colorectal cancer (CRC). In the …
personalized therapies for the treatment of cancer including colorectal cancer (CRC). In the …
Long non-coding RNA TPT1-AS1 suppresses APC transcription in a STAT1-dependent manner to increase the stemness of colorectal cancer stem cells
B Chen, H Sun, S Xu, Q Mo - Molecular Biotechnology, 2022 - Springer
Cancer stem cells (CSCs) are the major culprits leading to a new level of complexity and the
consequential therapy resistance and disease recurrence in colorectal cancer (CRC). This …
consequential therapy resistance and disease recurrence in colorectal cancer (CRC). This …
STAT1 is required for decreasing accumulation of granulocytic cells via IL-17 during initial steps of colitis-associated cancer
Y Delgado-Ramirez, I Baltazar-Perez… - International Journal of …, 2021 - mdpi.com
Signal transducer and activator of transcription 1 (STAT1) acts as a tumor suppressor
molecule in colitis-associated colorectal cancer (CAC), particularly during the very early …
molecule in colitis-associated colorectal cancer (CAC), particularly during the very early …