Effect of Plasmodium falciparum sulfadoxine-pyrimethamine resistance on the effectiveness of intermittent preventive therapy for malaria in pregnancy in Africa: a …

AM van Eijk, DA Larsen, K Kayentao… - The Lancet Infectious …, 2019 - thelancet.com
Summary Background Resistance of Plasmodium falciparum to sulfadoxine-pyrimethamine
threatens the antimalarial effectiveness of intermittent preventive treatment during …

Geographical spread and structural basis of sulfadoxine-pyrimethamine drug-resistant malaria parasites

R Chaturvedi, J Chhibber-Goel, I Verma… - International Journal for …, 2021 - Elsevier
The global spread of sulfadoxine (Sdx, S) and pyrimethamine (Pyr, P) resistance is attributed
to increasing number of mutations in DHPS and DHFR enzymes encoded by malaria …

Prevalence of Plasmodium falciparum haplotypes associated with resistance to sulfadoxine–pyrimethamine and amodiaquine before and after upscaling of seasonal …

KB Beshir, J Muwanguzi, J Nader… - The Lancet Infectious …, 2023 - thelancet.com
Background Seasonal malaria chemoprevention is used in 13 countries in the Sahel region
of Africa to prevent malaria in children younger than 5 years. Resistance of Plasmodium …

Drug-Resistance and Population Structure of Plasmodium falciparum Across the Democratic Republic of Congo Using High-Throughput Molecular Inversion Probes

O Aydemir, M Janko, NJ Hathaway… - The Journal of …, 2018 - academic.oup.com
A better understanding of the drivers of the spread of malaria parasites and drug resistance
across space and time is needed. These drivers can be elucidated using genetic tools. Here …

High throughput resistance profiling of Plasmodium falciparum infections based on custom dual indexing and Illumina next generation sequencing-technology

S Nag, MD Dalgaard, PE Kofoed, J Ursing, M Crespo… - Scientific reports, 2017 - nature.com
Genetic polymorphisms in P. falciparum can be used to indicate the parasite's susceptibility
to antimalarial drugs as well as its geographical origin. Both of these factors are key to …

High multiple mutations of Plasmodium falciparum-resistant genotypes to sulphadoxine-pyrimethamine in Lagos, Nigeria

H Quan, U Igbasi, W Oyibo, S Omilabu… - Infectious Diseases of …, 2020 - Springer
Background Plasmodium falciparum-resistance to sulphadoxine-pyrimethamine (SP) has
been largely reported among pregnant women. However, the profile of resistance markers to …

Antimalarial drug resistance in the Central and Adamawa regions of Cameroon: Prevalence of mutations in P. falciparum crt, Pfmdr1, Pfdhfr and Pfdhps genes

AGB Tuedom, EM Sarah-Matio, CEE Moukoko… - PLoS …, 2021 - journals.plos.org
The spread of Plasmodium falciparum resistant parasites remains one of the major
challenges for malaria control and elimination in Sub Saharan Africa. Monitoring of …

Plasmodium falciparum drug resistance-associated mutations in isolates from children living in endemic areas of Burkina Faso

CW Tarama, H Soré, M Siribié, S Débé, R Kinda… - Malaria Journal, 2023 - Springer
Background Artemisinin-based combinations therapy (ACT) is the current frontline curative
therapy for uncomplicated malaria in Burkina Faso. Sulfadoxine-pyrimethamine (SP) is used …

Effect of three years' seasonal malaria chemoprevention on molecular markers of resistance of Plasmodium falciparum to sulfadoxine-pyrimethamine and …

A Mahamar, KM Sumner, B Levitt, B Freedman… - Malaria journal, 2022 - Springer
Background In 2012, seasonal malaria chemoprevention (SMC) was recommended as
policy for malaria control by the World Health Organization (WHO) in areas of highly …

[HTML][HTML] Widespread resistance mutations to sulfadoxine-pyrimethamine in malaria parasites imported to China from Central and Western Africa

L Zhao, L Pi, Y Qin, Y Lu, W Zeng, Z Xiang, P Qin… - International Journal for …, 2020 - Elsevier
Background Imported cases of infectious disease provide invaluable information about
epidemiological conditions abroad, and should guide treatment decisions at home and …