Although stem cell-based therapy has demonstrated considerable potential to manage
certain diseases more successfully than conventional surgery, it nevertheless comes with …

Extracellular vesicles (eg, exosomes) carrying various biomolecules (eg, proteins, lipids,
and nucleic acids) have rapidly emerged as promising platforms for many biomedical …

Injury of oligodendrocytes (OLs) induces demyelination, and patients with
neurodegenerative diseases exhibit demyelination concomitantly with neurological deficit …

Cortical injury, such as injuries after stroke or age-related ischemic events, triggers a
cascade of degeneration accompanied by inflammatory responses that mediate …

Exosomes are natural cells-derived vesicles, which are at the forefront toward clinical
success for various diseases, including cerebral ischemia. Exosomes mediate cell-to-cell …

Background. Mesenchymal stem cell (MSC)-derived exosomes play a critical role in
regenerative medicine. Objective. To determine the dose-and time-dependent efficacy of …

Neurodegenerative disease refers to any pathological condition in which there is a
progressive decline in neuronal function resulting from brain atrophy. Despite the immense …

Ischaemic stroke is a leading cause of long-term disability in the world, with limited effective
treatments. Increasing evidence demonstrates that exosomes are involved in ischaemic …

The severity and long-term consequences of brain damage in traumatic brain injured (TBI)
patients urgently calls for better neuroprotective/neuroreparative strategies for this …

Exosomes play an important role in intercellular communication by delivering
microribonucleic acids (miRNAs) to recipient cells. Previous studies have demonstrated that …