Striatum is the potential target for treating absence epilepsy: a theoretical evidence

B Hu, W Zhou, X Ma - Cognitive Neurodynamics, 2024 - Springer
The output of the basal ganglia to the corticothalamic system plays an important role in
regulating absence seizures. Inspired by experiments, we systematically study the crucial …

The adjustment mechanism of the spike and wave discharges in thalamic neurons: a simulation analysis

B Hu, Z Wang, M Xu, D Zhang, D Wang - Cognitive Neurodynamics, 2022 - Springer
Different from many previous theoretical studies, this paper explores the regulatory
mechanism of the spike and wave discharges (SWDs) in the reticular thalamic nucleus …

The generation mechanism of spike-and-slow wave discharges appearing on thalamic relay nuclei

B Hu, Y Guo, F Shi, X Zou, J Dong, L Pan, M Yu… - Scientific Reports, 2018 - nature.com
In this paper, we use a model modified from classic corticothalamic network (CT) to explore
the mechanism of absence seizures appearing on specific relay nuclei (SRN) of the …

Control of absence epilepsy seizures in specific relay nuclei of thalamus

B Hu, X Zou, Y Guo, Z Yang, F Shi, W Dong - Journal of Theoretical Biology, 2017 - Elsevier
In this paper, we used a classic basal ganglia-corticothalamic model (BGCT) to study the
onset and control mechanism of absence epilepsy in specific relay nuclei (SRN) of …