Polygenic risk scores (PRSs) summarize the genetic predisposition of a complex human trait
or disease and may become a valuable tool for advancing precision medicine. However …

Polygenic risk scores (PRSs) are an emerging tool to predict the clinical phenotypes and
outcomes of individuals. We propose PRSmix, a framework that leverages the PRS corpus …

Precision diabetes medicine (PDM) aims to reduce errors in prevention programmes,
diagnosis thresholds, prognosis prediction and treatment strategies. However, its …

Attention problems are among the earliest precursors of schizophrenia (SCZ). Here we
examine relationships between multi-trait polygenic scores (PGS), psychotic spectrum …

Importance: By integrating genetic and clinical risk factors into genomic-informed dementia
risk reports, healthcare providers can offer patients detailed risk profiles to facilitate …

The genetic structure in Europe was mostly shaped by admixture between the Western
Hunter-Gatherer, Anatolian Neolithic and Steppe's Yamnaya ancestral components. Such …