miRNA dysregulation in cardiovascular diseases: current opinion and future perspectives

F Sessa, M Salerno, M Esposito, G Cocimano… - International Journal of …, 2023 - mdpi.com
MicroRNAs (miRNAs), small noncoding RNAs, are post-transcriptional gene regulators that
can promote the degradation or decay of coding mRNAs, regulating protein synthesis. Many …

Could artificial intelligence/machine learning and inclusion of diet-gut microbiome interactions improve disease risk prediction? Case study: coronary artery disease

B Vilne, J Ķibilds, I Siksna, I Lazda, O Valciņa… - Frontiers in …, 2022 - frontiersin.org
Coronary artery disease (CAD) is the most common cardiovascular disease (CVD) and the
main leading cause of morbidity and mortality worldwide, posing a huge socio-economic …

The miR‐126‐5p and miR‐212‐3p in the extracellular vesicles activate monocytes in the early stage of radiation‐induced vascular inflammation implicated in …

YY Choi, A Kim, Y Lee, YH Lee, M Park… - Journal of …, 2023 - Wiley Online Library
People exposed to radiation in cancer therapy and nuclear accidents are at increased risk of
cardiovascular outcomes in long‐term survivors. Extracellular vesicles (EVs) are involved in …

Identification of distinct circulating microRNAs in acute ischemic stroke patients with type 2 diabetes mellitus

SM Toor, EK Aldous, A Parray, N Akhtar… - Frontiers in …, 2022 - frontiersin.org
Stroke is the second leading cause of global mortality and continued efforts aim to identify
predictive, diagnostic, or prognostic biomarkers to reduce the disease burden. Circulating …

Inhibition of miR-194-5p avoids DUSP9 downregulation thus limiting sepsis-induced cardiomyopathy

J Wang, T Wei, W Zhang, Y Chu, D Zhang, M Zhang… - Scientific Reports, 2024 - nature.com
Sepsis-induced cardiomyopathy (SIC) is described as a reversible myocardial depression
that occurs in patients with septic shock. Increasing evidence shows that microRNA-194-5p …

Machine learning identifies new predictors on restenosis risk after coronary artery stenting in 10,004 patients with surveillance angiography

U Güldener, T Kessler, M von Scheidt, JS Hawe… - Journal of Clinical …, 2023 - mdpi.com
Objective: Machine learning (ML) approaches have the potential to uncover regular patterns
in multi-layered data. Here we applied self-organizing maps (SOMs) to detect such patterns …

The epigenetic role of MiRNAs in endocrine crosstalk between the cardiovascular system and adipose tissue: a bidirectional view

UPR Soci, BRR Cavalcante… - Frontiers in Cell and …, 2022 - frontiersin.org
Overweight and obesity (OBT) is a serious health condition worldwide, and one of the major
risk factors for cardiovascular disease (CVD), the main reason for morbidity and mortality …

Global alteration of colonic microRNAome landscape associated with inflammatory bowel disease

E Boros, Z Hegedűs, Z Kellermayer, P Balogh… - Frontiers in …, 2022 - frontiersin.org
Inflammatory Bowel Disease (IBD) is characterized by chronic inflammation of the
gastrointestinal tract that associates with, among others, increased risk of colorectal cancer …

Circulating exosome-derived miR-122-5p is a novel biomarker for prediction of postoperative atrial fibrillation

C Bai, Y Liu, Y Zhao, Q Ye, C Zhao, Y Liu… - Journal of cardiovascular …, 2022 - Springer
Postoperative atrial fibrillation (POAF) is a frequent complication associated with increased
periprocedural mortality and morbidity after cardiac surgery. Our study aimed to identify the …

[HTML][HTML] The Potential Contribution of MyomiRs miR-133a-3p,-133b, and-206 Dysregulation in Cardiovascular Disease Risk

P Crocco, A Montesanto, R La Grotta… - International …, 2024 - pmc.ncbi.nlm.nih.gov
Cardiovascular disease (CVD) is a major global health concern. The number of people with
CVD is expected to rise due to aging populations and increasing risk factors such as obesity …