Recent advances in combretastatin based derivatives and prodrugs as antimitotic agents
The dynamic and crucial role of tubulin in different cellular functions rendered it a promising
target in anticancer drug development. Combretastatin A-4 (CA-4), an inhibitor of tubulin …
target in anticancer drug development. Combretastatin A-4 (CA-4), an inhibitor of tubulin …
E-government maturity model for sustainable E-government services from the perspective of developing countries
Electric government (e-government) projects in developing countries are facing many
challenges to deliver sustainable e-government services. From the existing literature, we …
challenges to deliver sustainable e-government services. From the existing literature, we …
Pimenta dioica (L.) Merr. Bioactive Constituents Exert Anti-SARS-CoV-2 and Anti-Inflammatory Activities: Molecular Docking and Dynamics, In Vitro, and In Vivo …
In response to the urgent need to control Coronavirus disease 19 (COVID-19), this study
aims to explore potential anti-SARS-CoV-2 agents from natural sources. Moreover, cytokine …
aims to explore potential anti-SARS-CoV-2 agents from natural sources. Moreover, cytokine …
The microwave-assisted syntheses and applications of non-fused single-nitrogen-containing heterocycles
Microwave technology has emerged as a great tool for the efficient synthesis of organic
compounds and it provides opportunities for chemists to achieve chemical transformations …
compounds and it provides opportunities for chemists to achieve chemical transformations …
Novel indole-pyrazole hybrids as potential tubulin-targeting agents; Synthesis, antiproliferative evaluation, and molecular modeling studies
Abstract Structurally diverse indole-3-pyrazole-5-carboxamide analogues (10-29) were
designed, synthesized, and evaluated for their antiproliferative activity against three cancer …
designed, synthesized, and evaluated for their antiproliferative activity against three cancer …
[PDF][PDF] Key factors for e-government towards sustainable development goals
The emergence of numerous innovations promotes the development of information and
communication technology (ICT) in many countries and changes the way government …
communication technology (ICT) in many countries and changes the way government …
Exploring the Landscape of e-Government Maturity Models: Insights from Systematic Mapping Study and Comparative Analysis
AA Okan - Digital Government: Research and Practice, 2024 - dl.acm.org
e-Government Maturity Models are essential tools for governments to assess and improve
their e-government capabilities, performance, and impact. This article offers a pioneering …
their e-government capabilities, performance, and impact. This article offers a pioneering …
Synthesis and antiproliferative evaluation of 3-chloroazetidin-2-ones with antimitotic activity: Heterocyclic bridged analogues of combretastatin a-4
AM Malebari, S Wang, TF Greene, NM O'boyle… - Pharmaceuticals, 2021 - mdpi.com
Antimitotic drugs that target tubulin are among the most widely used chemotherapeutic
agents; however, the development of multidrug resistance has limited their clinical activity …
agents; however, the development of multidrug resistance has limited their clinical activity …
Design, synthesis and screening of 4, 6-diaryl pyridine and pyrimidine derivatives as potential cytotoxic molecules
Chem. Pharm. Bull. 66(10): 939-952 (2018) Page 1 © 2018 The Pharmaceutical Society of Japan
Vol. 66, No. 10 939 Chem. Pharm. Bull. 66, 939–952 (2018) Regular Article Design, Synthesis …
Vol. 66, No. 10 939 Chem. Pharm. Bull. 66, 939–952 (2018) Regular Article Design, Synthesis …
Combretastatin A-4 based compounds as potential anticancer agents: A review
The current review discusses the importance of combretastatin A-4 (CA-4) as a lead
compound of microtubule targeting agents. CA-4 holds a unique place among naturally …
compound of microtubule targeting agents. CA-4 holds a unique place among naturally …