Polymeric micelles are demonstrating high potential as nanomedicines capable of controlling the distribution and function of loaded bioactive agents in the body, effectively …
J Li, K Kataoka - Journal of the American Chemical Society, 2020 - ACS Publications
The past few decades have witnessed an evolution of nanomedicine from biologically inert entities to more smart systems, aimed at advancing in vivo functionality. However, we should …
C Qian, J Yu, Y Chen, Q Hu, X Xiao, W Sun… - … (Deerfield Beach, Fla …, 2016 - ncbi.nlm.nih.gov
A light-activated hypoxia-responsive conjugated polymer-based nanocarrier is developed for efficiently producing singlet oxygen (1O2) and inducing hypoxia to promote release of its …
Indocyanine green (ICG) is a near-infrared dye that has been used in the clinic for retinal angiography, and defining cardiovascular and liver function for over 50 years. Recently …
Hypoxia is a salient feature observed in most solid malignancies that holds a pivotal role in angiogenesis, metastasis and resistance to conventional cancer therapeutic approaches …
Photodynamic therapy (PDT) is a clinical modality used to treat cancer and infectious diseases. The main agent is the photosensitizer (PS), which is excited by light and converted …
AY Rwei, W Wang, DS Kohane - Nano today, 2015 - Elsevier
Externally triggerable drug delivery systems provide a strategy for the delivery of therapeutic agents preferentially to a target site, presenting the ability to enhance therapeutic efficacy …
N Fomina, J Sankaranarayanan, A Almutairi - Advanced drug delivery …, 2012 - Elsevier
Over the last three decades, a handful of photochemical mechanisms have been applied to a large number of nanoscale assemblies that encapsulate a payload to afford spatio …
G Mayer, A Heckel - Angewandte Chemie International Edition, 2006 - Wiley Online Library
Biologically active compounds which are light‐responsive offer experimental possibilities which are otherwise very difficult to achieve. Since light can be manipulated very precisely …